189631-96-7

Basic information

• Product Name: Butanoic acid, 2-amino-2-ethyl-, ethyl ester
• Synonyms: Butanoic acid, 2-amino-2-ethyl-, ethyl ester
• CAS NO: 189631-96-7
• Molecular Formula: C₈H₁₇NO₂
• Molecular Weight: 159.23
• Mol File: 189631-96-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Butanoic acid, 2-amino-2-ethyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-amino-2-ethyl-, ethyl ester(189631-96-7)
• EPA Substance Registry System: Butanoic acid, 2-amino-2-ethyl-, ethyl ester(189631-96-7)

Safety Data

• Hazardous Substances Data: 189631-96-7(Hazardous Substances Data)

Upstream product

• 96-22-0 pentan-3-one 
• 510-20-3 diethyl malonic acid 
• 5456-23-5 2-ethyl-2-bromo-butyric acid 
• 22374-51-2 1-amino-1-ethylpropyl cyanide 
• 126385-72-6 ethyl 2-[(4-chlorobenzylidene)amino]butanoate 
• 64-17-5 ethanol 
• 92398-53-3 α,α-diethylglycine hydrochloride 
• 189631-94-5 ethyl 2-[(diphenylmethylene)amino]-2-ethylbutanoate 
• 2566-29-2 diethylglycine 

Downstream Products

• 1007232-80-5 4-(2-{[1-ethyl-1-(hydroxymethyl)propyl]amino}-1,3-thiazol-4-yl)benzonitrile 
• 1007232-78-1 N-({[1-ethyl-1-(hydroxymethyl)propyl]amino}carbonothioyl)benzamide 
• 2566-29-2 diethylglycine 
• 19792-52-0 2-amino-2-ethylbutan-1-ol 

Relevant articles and documents

Helical versus planar conformation of homooligopeptides prepared from diethylglycine (= 2-amino-2-ethylbutanoic acid)

Homooligopeptides containing α,α-diethylgycine (=2-amino-2- ethylbutanoic acid), were synthesized by conventional solution methods. An ethyl or methyl ester was used as protecting group at the C-terminus and a trifluoroacetyl group as protecting group at the N-terminus of the peptides. The conformations of such tripenta-, and hexapeptides in the solid state were studied using X-ray crystallographic analysis, and were shown to be a bent planar C5-conformation in the case of tripeptide 8a, and a 310-helical structure in the case of pentapeptide 10 and hexapeptide 11. 1R and 1H-NMR spectra revealed that the dominant conformation of hexapeptide 11 in CDCl3 solution was not the 310-helical structure shown in the solid state, but a fully planar C5 structure.

Pyrrolidine and related derivatives useful as PR modulators

Compounds of the following structure are described: wherein R1-R6, R11, R12, m, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compou

Oxazolidone derivatives as PR modulators

Compounds of the following structure are described: wherein R1, R2, R5, R6, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are useful for treating a variety of hormone-related conditions including contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake or synchronizing estrus.