189680-99-7

Upstream product

• 171178-46-4 5-[N-(tert-butoxycarbonyl)amino]-2-chloropyridine-4-carboxylic acid 
• 171178-45-3 tert-butyl (6-chloropyridin-3-yl)carbamate 
• 58483-95-7 5‐amino‐2‐chloropyridine‐4‐carboxylic acid 
• 171178-47-5 6-chloro-3H-pyrido[3,4-d]pyrimidin-4-one 
• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 189680-98-6 6-dimethylamino-3H-pyrido[3,4-d]pyrimidin-4-one 

Downstream Products

• 189680-69-1 6-(N,N-Dimethylamino)-4-[4-(1-phenyl-1,2-dioxoethyl-2-yl)anilino]-pyrido[3,4-d]pyrimidine hydrochloride 
• 202273-13-0 N₄-(1-(2-Fluoro-benzyl)-1H-indazol-5-yl)-N₆,N₆-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine hydrochloride 
• 189680-67-9 4-(4-Benzyloxy-3-chloroanilino)-6-(N,N-dimethylamino)pyrido[3,4-d]pyrimidine hydrochloride 
• 202273-14-1 N₄-(1-(3-Fluoro-benzyl)-1H-indazol-5-yl)-N₆,N₆-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine hydrochloride 
• 202273-16-3 N₄-(1-Benzenesulphonyl-1H-indol-5-yl)-N₆,N₆-dimethyl-pyrido[3,4-d]pyrimidine-4,6-diamine hydrochloride 
• 189680-68-0 6-(N,N-Dimethylamino)-4-[4-(1-phenyl-1-cyanomethyl)anilino]pyrido[3,4-d]pyrimidine hydrochloride 
• 202272-68-2 GW2974 

Relevant academic research and scientific papers

Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2

Described herein is the design and synthesis of indazolylaminopyridopyrimidines and quinazolines as inhibitors of the class 1 tyrosine kinase receptor family. Data is presented for N4-(1-benzyl-1H-indazol-5-yl)-N6,N6- dime