Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2

DOI: 10.1016/S0960-894X(01)00219-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1401 - 1405 (2001)

Update date:2022-09-26

Topics:

Authors:

Cockerill, Stuart

Stubberfield, Colin

Stables, Jeremy

Carter, Malcolm

Guntrip, Stephen

Smith, Kathryn

McKeown, Steve

Shaw, Robert

Topley, Peter

Thomsen, Lindy

Affleck, Karen

Jowett, Amanda

Hayes, David

Willson, Malcolm

Woollard, Patrick

Spalding, David

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Article abstract of DOI:10.1016/S0960-894X(01)00219-0

Described herein is the design and synthesis of indazolylaminopyridopyrimidines and quinazolines as inhibitors of the class 1 tyrosine kinase receptor family. Data is presented for N⁴-(1-benzyl-1H-indazol-5-yl)-N⁶,N⁶- dime

Full text of DOI:10.1016/S0960-894X(01)00219-0

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