189766-46-9Relevant academic research and scientific papers
Improved Synthesis of the Enantiomers of Propafenone Using Chiral Building Blocks
Ecker,Noe,Fleischhacker
, p. 53 - 59 (1997)
A short and efficient synthesis of the enantiomers of the antiarrhythmic drug propafenone (1) is described using both (R)-isopropylideneglycerol tosylate and (S)-glycidyl tosylate as chiral building blocks. The key step of the high yield synthesis is the
