Monatshefte fur Chemie p. 53 - 59 (1997)
Update date:2022-08-05
Topics:
Ecker
Noe
Fleischhacker
A short and efficient synthesis of the enantiomers of the antiarrhythmic drug propafenone (1) is described using both (R)-isopropylideneglycerol tosylate and (S)-glycidyl tosylate as chiral building blocks. The key step of the high yield synthesis is the
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Doi:10.1016/S0040-4039(00)78485-1
(1994)Doi:10.1016/S0960-894X(97)00115-7
(1997)Doi:10.1021/jo970067d
(1997)Doi:10.1016/S0040-4039(97)00728-4
(1997)Doi:10.1016/S0960-894X(97)00189-3
(1997)Doi:10.1021/ol030084r
(2003)
