190059-57-5

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 161821-04-1 9,18,2'-tri-O-tert-butyldimethylsilylleucomycin A₇ 3,18-acetal 
• 100-39-0 benzyl bromide 
• 161821-05-2 9,18,2'-tri-O-tert-butyldimethylsilylleucomycin V 3,18-acetal 

Downstream Products

• 190059-66-6 4''-O-benzyl-9,18-di-O-tert-butyldimethylsilyl-3''-O-methylleucomycin V 3,18-acetal 

Relevant academic research and scientific papers

Cladinose analogues of sixteen-membered macrolide antibiotics III. Efficient synthesis of 4-0-alky-L-cladinose analogues: Improved antibacterial activities compatible with pharmacokinetics

The synthesis and biological evaluation of sixteen-membered macrolides possessing a 4-0-alkyl-α-L-cladinosyl moiety as a neutral sugar are described. These potent novel derivatives have been efficiently synthesized avoiding glycosylations. Two hydroxyl gr