190086-12-5

Basic information

• Product Name: SOLVENT YELLOW 93
• Synonyms: 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4h-pyrazol-4-ylidene)methyl]-2,4-dihydro-5-methyl-2-phenyl-3h-pyrazol-3-one;Oil Yellow 93
• CAS NO: 190086-12-5
• Molecular Formula: C21H18N4O2
• Molecular Weight: 358.39322
• EINECS: 225-184-1
• Mol File: 190086-12-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: SOLVENT YELLOW 93(CAS DataBase Reference)
• NIST Chemistry Reference: SOLVENT YELLOW 93(190086-12-5)
• EPA Substance Registry System: SOLVENT YELLOW 93(190086-12-5)

Safety Data

• Hazardous Substances Data: 190086-12-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 525-58-6 3-[3H-indol-3-ylidenemethyl]-1H-indole 
• 89-25-8 edaravone 
• 151-50-8 potassium cyanide 
• 4173-70-0 1-phenyl-3-methyl-4-methylaminomethylene-5-pyrazolone 
• 4942-70-5 4-(dimethylaminomethylene)-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 947-95-5 5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole 
• 109-77-3 malononitrile 
• 51751-34-9 4-hydroxycoumarin-3-carboxaldehyde 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 122-51-0 orthoformic acid triethyl ester 
• 193696-10-5 1,3-Dimethyl-2,4-dioxo-6-pyrrolidin-1-yl-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde 
• 35824-85-2 6-chloro-5-formyl-1,3-dimethyluracil 
• 114143-07-6 6-(Allyl-phenyl-amino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde 

Relevant articles and documents

A mild and efficient method for the deformylation of 5-formyl uracils and synthesis of 4,4￠-methylidenebis(1-phenyl-3-methyl-5-pyrazolone)

6-Substituted 5-formyl uracils undergo an interesting reaction with 1-phenyl-3-methyl-5-pyrazolone in the presence of base catalyst to afford deformylated uracils and 4,4￠-methylidenebis(1-phenyl-3-methyl-5- pyrazolone) in excellent yields. Georg Thieme V

Novel reactions of 5-chloro-4-formyl-3-methyl-1-phenylpyrazole with active methylene compounds

Condensation of 5-chloro-4-formyl-3-methyl-1-phenylpyrazole (1) with malononitrile in the presence of piperidine or ammonium acetate affords the corresponding pyrazole derivatives (2-4). Base-catalyzed cyclocondensation of 1 with hippuric acid or ethyl glycinate hydrochloride gives the oxazolone 6 and 5-amino-3-methyl-6-oxo-1-phenyl-1,6-dihydropyrano[2,3-c]pyrazole (7) respectively. Treatment of 1 with ethyl cyanoacetate in basic medium produce ethyl α-cyano-β-(5-chloro-3-methyl-1-phenylpyrazol-4-yl)acrylate (8) which reacts with nitrogen nucleophiles to give compounds 9-12. Transesterification and/or hydrolysis of ester group has been observed on treatment of 8 with methyl alcohol in basic medium leading to the formation of acrylate derivatives (13-15). Compound 8 on treatment with ethyl acetoacetate or cyclohexanone undergoes condensation with subsequent cyclization and/or dearylation to give the adducts 16 and 17 respectively. Structures of all the products have been established by elemental analysis, IR, PMR and mass spectral data.