190127-10-7Relevant academic research and scientific papers
The first selective antagonist for a GABAC receptor
Murata, Yoshinori,Woodward, Richard M.,Miledi, Ricardo,Overman, Larry E.
, p. 2073 - 2076 (1996)
(1,2,5,6-Tetrahydropyridine-4-yl)methylphosphinic acid (TPMPA, 1), which is synthesized in six steps from 3-butyn-1-ol, is the first γ-aminobutyric acid (GABA) receptor antagonist that shows strong selectivity for mammalian GABAc receptors. Copyright
