1902-95-0

Upstream product

• 27975-74-2 ethyl-(α-chloro-benzyl)-ether 
• 925-90-6 ethylmagnesium bromide 
• 693-02-7 hex-1-yne 
• 64-17-5 ethanol 
• 111833-50-2 1-phenylhept-2-ynyl acetate 
• 774-48-1 (diethoxymethyl)benzene 
• 73922-80-2 1-phenylhept-2-yn-1-ol 
• 100-52-7 benzaldehyde 

Downstream Products

• 5595-63-1 1-phenyl-2-hepten-1-one 
• 1071001-96-1 1-Ethoxy-1-phenyl-hepta-1,2-dien 

Relevant academic research and scientific papers

BiCl3-catalyzed propargylic substitution reaction of propargylic alcohols with C-, O-, S- and N-centered nucleophiles

A general and efficient BiCl3-catalyzed substitution reaction of propargylic alcohols with carbon and heteroatom-centered nucleophiles such as allyl trimethylsilane, alcohols, aromatic compounds, thiols and amides, leading to the construction o

Metal-free catalytic nucleophilic substitution of propargylic alcohols

Organic acids such as PTS efficiently catalyze direct nucleophilic substitutions of the hydroxy groups of propargylic alcohols with a large variety of carbon- and heteroatom-centered nucleophiles. Reactions can be conducted under mild conditions and in air without the need for dried solvents. Reactions on multigram scales are also possible. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

A general and efficient FeCl3-catalyzed nucleophilic substitution of propargylic alcohols

A general and efficient FeCl3-catalyzed substitution reaction of propargylic alcohols with carbon- and heteroatom-centered nucleophiles such as allyl trimethylsilane, alcohols, aromatic compounds, thiols, and amides, leading to the construction of C-C, C-O, C-S and C-N bonds, has been developed.

FeCl3-catalyzed coupling of propargylic acetates with alcohols

A new method for the synthesis of propargylic ethers by FeCl 3-catalyzed alcoholysis of propargylic acetates was developed. The reaction was carried out at room temperature in acetonitrile without exclusion of moisture or air. High product yiel

TiCl4-mediated nucleophilic substitution of propargylic esters

Direct displacement reactions of propargylic esters are reported. 10 mol% of TiCl4 were used to carry out a nucleophilic substitution. Scope and limitation of this novel reaction are described. (C) 2000 Elsevier Science Ltd.

Synthesis of propargylic ethers via Lewis-acid mediated nucleophilic substitution of propargylic esters

Direct displacement of propargylic esters is reported 10 mol% of TiCl4 were used to carry out this novel, nucleophilic substitution.