19025-38-8Relevant articles and documents
Photo-irradiation of α-halo carbonyl compounds: A novel synthesis of α-hydroxy- and α,α′-dihydroxyketones
Chai, Wen,Takeda, Akihiro,Hara, Makoto,Ji, Shun-Jun,Horiuchi, C. Akira
, p. 2453 - 2463 (2007/10/03)
The reaction of α-halo ketones (α-iodocycloalkanones, α-bromocycloalkanones, α-iodo-β-alkoxy esters, and α-iodoacyclicketones) with irradiation under a high-pressure mercury lamp gave the corresponding α-hydroxyketones in good yields. For α-bromoketones, it was found that α-hydroxylation does not occur. However, α-bromoketones were converted into α-hydroxyketones in the presence of KI. In the case of α,α′-diiodo ketones, α,α′-dihydroxyketones, which up to now have scarcely been reported, were obtained. This reaction affords a new, clean and convenient synthetic method for α-hydroxy- and α,α′- dihydroxyketones.
Synthesis of α,β-unsaturated ketone from α-iodo ketone using photoirradiation
Ji, Shun-Jun,Takahashi, Eiji,Takahashi, T. Tomoyoshi,Horiuchi, C. Akira
, p. 9263 - 9266 (2007/10/03)
Irradiation of α-iodo ketone in hexane under a nitrogen atmosphere with a high-pressure mercury lamp (λ>300nm) at room temperature afforded the corresponding α,β-unsaturated ketones in good yield. This reaction affords a new, clean and convenient synthetic method for the α,β-unsaturated ketone.
Acid-Catalyzed Oxidation of Oxiranes with Dimethyl Sulfoxide Giving α-Hydroxy Ketones
Tsuji, Tadakazu
, p. 645 - 647 (2007/10/02)
The reaction of various oxiranes with dimethyl sulfoxide in the presence of Molecular Sieve 4A and acid afforded the corresponding α-hydroxy ketones.The molecular sieve found to accelerate the reaction.