190319-70-1

Basic information

• Product Name: 3-Pyridinecarboxamide, 2-amino-6-(4-chlorophenyl)-4-(4-fluorophenyl)-
• CAS NO: 190319-70-1
• Molecular Formula: C18H13ClFN3O
• Molecular Weight: 341.772
• Mol File: 190319-70-1.mol

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, 2-amino-6-(4-chlorophenyl)-4-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, 2-amino-6-(4-chlorophenyl)-4-(4-fluorophenyl)-(190319-70-1)
• EPA Substance Registry System: 3-Pyridinecarboxamide, 2-amino-6-(4-chlorophenyl)-4-(4-fluorophenyl)-(190319-70-1)

Safety Data

• Hazardous Substances Data: 190319-70-1(Hazardous Substances Data)

Upstream product

• 126443-14-9 1-(4-chlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one 
• 160031-97-0 2-amino-3-cyano-6-(4-chlorophenyl)-4-(4-fluorophenyl)pyridine 

Downstream Products

• 281225-35-2 7-(4-chloro-phenyl)-5-(4-fluoro-phenyl)-3-(2-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 281225-36-3 7-(4-chloro-phenyl)-5-(4-fluoro-phenyl)-3-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Synthesis of ribonucleosides of 2-thioxopyrido [2,3-d]pyrimidines by phase transfer catalysis and their antimicrobial activity

The ribonucleosides viz; 2-thioxo-3,5,7-trisubstituted-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl) pyrido[2,3-d]pyrimidine-4 (1H)-ones have been synthesized via phase transfer ribosylation of 2-thioxo- 3,5,7-trisubstituted pyrido[2,3-d)pyrimidine-4(1H)-ones with 2,3,5-tri-O-benzoyl-β-D- ribofuranosyl bromide in biphasic solvent such as CH2Cl2-50% aqueous NaOH using tetrabutylammonium bromide as phase transfer catalysis (PTC). The synthesized compounds have been characterized by elemental analyses, spectral data and screened for their antimicrobial activity.