281225-35-2

Upstream product

• 160031-97-0 2-amino-3-cyano-6-(4-chlorophenyl)-4-(4-fluorophenyl)pyridine 
• 126443-14-9 1-(4-chlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one 
• 3288-04-8 1-isothiocyanato-2-methoxybenzene 
• 190319-70-1 2-amino-6-(4-chloro-phenyl)-4-(4-fluoro-phenyl)-nicotinamide 

Relevant academic research and scientific papers

Synthesis of ribonucleosides of 2-thioxopyrido [2,3-d]pyrimidines by phase transfer catalysis and their antimicrobial activity

The ribonucleosides viz; 2-thioxo-3,5,7-trisubstituted-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl) pyrido[2,3-d]pyrimidine-4 (1H)-ones have been synthesized via phase transfer ribosylation of 2-thioxo- 3,5,7-trisubstituted pyrido[2,3-d)pyrimidine-4(1H)-ones with 2,3,5-tri-O-benzoyl-β-D- ribofuranosyl bromide in biphasic solvent such as CH2Cl2-50% aqueous NaOH using tetrabutylammonium bromide as phase transfer catalysis (PTC). The synthesized compounds have been characterized by elemental analyses, spectral data and screened for their antimicrobial activity.