190654-87-6Relevant academic research and scientific papers
2,6,9-Trisubstituted purines: Optimization towards highly potent and selective CDK1 inhibitors
Imbach, Patricia,Capraro, Hans-Georg,Furet, Pascal,Mett, Helmut,Meyer, Thomas,Zimmermann, Juerg
, p. 91 - 96 (2007/10/03)
Novel 2,6,9-substituted purine derivatives represent a class of potent and selective inhibitors of CDK1/cyclinB. The synthesis, SAR and biological profile of selected compounds are described.
