19066-35-4

Basic information

• Product Name: 5,7-Diphenyl-1,3-diazatricyclo[3.3.1.13,7]decan-6-one
• Synonyms: 1,5-Diphenyl-3,7-diazaadamantan-9-one;5,7-Diphenyl-1,3-diazatricyclo[3.3.1.13,7]decan-6-one;5,7-diphenyl-1,3-diazatricyclo[3.3.1.1,]decan-6-one;(1r,3r,5r,7r)-5,7-diphenyl-1,3-diazaadamantan-6-one
• CAS NO: 19066-35-4
• Molecular Formula: C₂₀H₂₀N₂O
• Molecular Weight: 304.3856
• Mol File: 19066-35-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 484.9°Cat760mmHg
• Flash Point: 218.9°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 1.48E-09mmHg at 25°C
• Refractive Index: 1.692
• CAS DataBase Reference: 5,7-Diphenyl-1,3-diazatricyclo[3.3.1.13,7]decan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-Diphenyl-1,3-diazatricyclo[3.3.1.13,7]decan-6-one(19066-35-4)
• EPA Substance Registry System: 5,7-Diphenyl-1,3-diazatricyclo[3.3.1.13,7]decan-6-one(19066-35-4)

Safety Data

• Hazardous Substances Data: 19066-35-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H20N2O/c23-18-20(17-9-5-2-6-10-17)11-19(16-7-3-1-4-8-16)12-21(14-20)15-22(18)13-19/h1-10H,11-15H2

Upstream product

• 100-97-0 hexamethylenetetramine 
• 102-04-5 1,3-Diphenylpropanone 
• 50-00-0 formaldehyd 
• 13638-71-6 9-oxo-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonane-3,7-dicarboxylic acid diethyl ester 
• 631-61-8 ammonium acetate 
• 57164-14-4 1,5-diphenyl-3,7-diazabicyclo<3.3.1>nonan-9-one 

Downstream Products

• 1053242-62-8 C₂₇H₂₈N₂O₅ 
• 1604777-55-0 sodium 6-oxo-5,7-diphenyl-1,3-diaza-2-phospha-tricyclo[3.3.1.1^3,7]decan-2-olate 2-oxide 
• 1604777-44-7 2-chloro-5,7-diphenyl-1,3-diaza-2-phospha-tricyclo[3.3.1.1^3,7]decane-6-one 2-oxide 
• 14930-85-9 5,7-diphenyl-1,3-diaza-2-thia-tricyclo[3.3.1.1^3,7]decan-6-one 2-oxide 
• 57164-14-4 1,5-diphenyl-3,7-diazabicyclo<3.3.1>nonan-9-one 
• 103566-81-0 3,7-bis-(2-dimethylamino-ethyl)-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonan-9-ol 
• 115000-34-5 3,7-bis-(N,N-dimethyl-glycyl)-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonan-9-one 
• 103328-41-2 3,7-dibenzoyl-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonane 
• 79168-89-1 3,7-diacetyl-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonan-9-one 
• 104115-61-9 3,7-diacetyl-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonane 
• 109094-59-9 3,7-dinitroso-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonan-9-ol 
• 102082-13-3 3,7-dinitroso-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonane 
• 113862-18-3 3,7-diethyl-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonan-9-ol 
• 102163-85-9 1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]nonane 

Relevant articles and documents

Anti-neoplastic activity of 1,3-diaza-2-functionalized-adamantan-6-one compounds against melanoma cells

Four series of 1,3-diaza-2-functionalized-adamantan-6-one derivatives, bearing at the 2 position SO, SO2, POCl and PO2H functional groups, were synthesized via a key quadruple Mannich reaction, followed by transformation of an aminal functionality into th

Synthesis of novel diazabicycles and their antiprotozoal activities

We describe the synthesis of new diaryl substituted diazabicyclo[3.2.1] octanes from diazepanes which were prepared by the reduction of diazepanones. The formation of the bicyclic system was optimized by microwave irradiation and the structures of the new compounds were established by single crystal structure analysis and NMR spectroscopy. All new compounds were tested for their potencies against Plasmodium falciparum K1 and Trypanosoma b. rhodesiense, the causative organisms of malaria tropica and the East African form of sleeping sickness. CSIRO 2009.

Conformational Control in the 3,7-Diazabicyclononane System

The twin-chair or boat-chair conformation of 3,7-diazabicyclononanes can be selected by forming N,N'-derivatives in which the N atoms have planar or pyramidal bonding patterns, respectively, e.g., acyl substituents for the former and arylsulphonyl