19066-35-4Relevant academic research and scientific papers
Anti-neoplastic activity of 1,3-diaza-2-functionalized-adamantan-6-one compounds against melanoma cells
Sharabi-Ronen, Yifat,Levinger, Shlomo,Lellouche, Miri Ben-Dahan,Albeck, Amnon
, p. 27 - 37 (2014/01/17)
Four series of 1,3-diaza-2-functionalized-adamantan-6-one derivatives, bearing at the 2 position SO, SO2, POCl and PO2H functional groups, were synthesized via a key quadruple Mannich reaction, followed by transformation of an aminal functionality into th
2,6-DIPHENYL-4,8-DIAZOADAMANTAN-1-ONE AND DERIVATIVES THEREOF, PROCESS OF MANUFACTURE AND USE FOR THE FORMULATION OF SOLUTIONS WITH STERILIZING AND DISINFECTANT EFFECT
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Page/Page column 1-2, (2010/04/23)
A chemical compound having the following structural formula wherein optionally at least one of the phenyl —C6H5 groups bound to the Carbon atoms in position 2 and 6 is independently substituted with a methyl —CH3 or ethyl
Synthesis of novel diazabicycles and their antiprotozoal activities
Wolkinger, Volker,Weis, Robert,Belaj, Ferdinand,Kaiser, Marcel,Brun, Reto,Saf, Robert,Seebacher, Werner
body text, p. 1166 - 1172 (2010/03/04)
We describe the synthesis of new diaryl substituted diazabicyclo[3.2.1] octanes from diazepanes which were prepared by the reduction of diazepanones. The formation of the bicyclic system was optimized by microwave irradiation and the structures of the new compounds were established by single crystal structure analysis and NMR spectroscopy. All new compounds were tested for their potencies against Plasmodium falciparum K1 and Trypanosoma b. rhodesiense, the causative organisms of malaria tropica and the East African form of sleeping sickness. CSIRO 2009.
Structural and spatial considerations in the N,N′-diacyl- and bis(alkoxycarbonyl)bispidinone series
Levinger, Shlomo,Sharabi-Ronen, Yifat,Mainfeld, Alexander,Albeck, Amnon
, p. 7793 - 7796 (2008/12/22)
(Chemical Equation Presented) Diamidic and dicarbamic bispidinones show trans-cis isomerism, the relative population in solution of the cis form increasing with solvent polarity. The mutual proximity of the two amide functions in 4a has no impact on the b
HETEROADAMANTANES AND THEIR DERIVATIVES. 6. SYNTHESIS AND MASS-SPECTROMETRIC INVESTIGATION OF 5-MONO- AND 5,6-DISUBSTITUTED 6-OXO-1,3-DIAZAADAMANTANES
Kuznetsov, A. I.,Basargin, E. B.,Moskovkin, A. S.,Ba, M. Kh.,Miroshnichenko, I. V.,et al.
, p. 1382 - 1388 (2007/10/02)
The corresponding 5-mono and 5,7-disubstituted 6-oxo-1,3-diazaadamantanes were obtained with high yields by the condensation of mono and α,α'-disubstituted acetones with hexamethylenetetramine in the presence of glacial acetic acid, and their structures w
Conformational Control in the 3,7-Diazabicyclononane System
McCabe, P. H.,Milne, N. J.,Sim, G. A.
, p. 625 - 626 (2007/10/02)
The twin-chair or boat-chair conformation of 3,7-diazabicyclononanes can be selected by forming N,N'-derivatives in which the N atoms have planar or pyramidal bonding patterns, respectively, e.g., acyl substituents for the former and arylsulphonyl
