190730-40-6

Basic information

• Product Name: 1-(2-hydroxy-3-methyl-4-nitrophenyl)ethanone
• Synonyms: 1-(2-hydroxy-3-methyl-4-nitrophenyl)ethanone
• CAS NO: 190730-40-6
• Molecular Weight: 195.175
• Mol File: 190730-40-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2-hydroxy-3-methyl-4-nitrophenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxy-3-methyl-4-nitrophenyl)ethanone(190730-40-6)
• EPA Substance Registry System: 1-(2-hydroxy-3-methyl-4-nitrophenyl)ethanone(190730-40-6)

Safety Data

• Hazardous Substances Data: 190730-40-6(Hazardous Substances Data)

Upstream product

• 5460-31-1 3-nitro-o-cresol 
• 75-36-5 acetyl chloride 

Downstream Products

• 210171-45-2 Toluene-4-sulfonic acid (R)-8-oxo-2,3,4,7,8,9-hexahydro-pyrano[2,3-e]indol-2-ylmethyl ester 
• 210171-46-3 Toluene-4-sulfonic acid (S)-8-oxo-2,3,4,7,8,9-hexahydro-pyrano[2,3-e]indol-2-ylmethyl ester 
• 190730-49-5 2-(p-tolylsulfonylmethyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one 

Relevant articles and documents

New generation dopaminergic agents 4. Exploiting the 2-methyl chroman scaffold. Synthesis and evaluation of two novel series of 2-(aminomethyl)- 3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indol-8-one derivatives

The rational design, synthesis, and evaluation of two novel series of 2- (aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indolone derivatives are disclosed, based on the recently discovered D2 agonist phenolic template prototype [i.e. the 7-OH-2-(aminomethyl)chroman nucleus]. The indolones were observed to have higher affinity and intrinsic activity than the corresponding indoles.

2-(AMINOMETHYL)-3,4,7,9-TETRAHYDRO-2H-PYRANO-[2,3-E]INDOL-8-ONES AND DERIVATIVES

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