Tetrahedron p. 7081 - 7108 (1998)
Update date:2022-08-03
Topics:
Mewshaw, Richard E.
Marquis, Karen L.
Shi, Xiaojie
McGaughey, Georgia
Stack, Gary
Webb, Michael B.
Abou-Gharbia, Magid
Wasik, Theodore
Scerni, Rosemary
Spangler, Taylor
Brennan, Julie A.
Mazandarani, Hossein
Coupet, Joseph
Andree, Terrance H.
The rational design, synthesis, and evaluation of two novel series of 2- (aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indolone derivatives are disclosed, based on the recently discovered D2 agonist phenolic template prototype [i.e. the 7-OH-2-(aminomethyl)chroman nucleus]. The indolones were observed to have higher affinity and intrinsic activity than the corresponding indoles.
View MoreJiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd
Contact:+86-0517-87036900
Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Shanghai shibo Chemical Co., Ltd
Contact:+86-021-60753516
Address:688 Qiushi Road, Jinshan High-tech Park, Shanghai, China,201512
Jiangyin Tenghua Import&Export Co.,Ltd.
Contact:+86-510-86263875
Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
Contact:18698110882
Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd
Contact:+86-311-80817929
Address:Shangzhuang,Shijiazhuang,China
Doi:10.1016/S0040-4020(97)00296-2
(1997)Doi:10.1021/om970522w
(1998)Doi:10.1002/jhet.5570340246
(1997)Doi:10.1002/anie.199709951
(1997)Doi:10.1016/j.tet.2015.06.035
(2015)Doi:10.1021/ja964113n
(1997)