190774-07-3Relevant articles and documents
Synthesis, structure, and structure-activity relationship analysis of enamines as potential antibacterials
Xiao, Zhu-Ping,Xue, Jia-Yu,Tan, Shu-Hua,Li, Huan-Qiu,Zhu, Hai-Liang
, p. 4212 - 4219 (2007)
Twenty-four enamines were synthesized and reported for the first time. Their chemical structures were confirmed by means of 1H NMR, ESI mass spectra, and elemental analyses, and four of them were determined by single crystal X-ray diffraction a
Synthesis and anticancer evaluation of 3-substituted quinolin-4-ones and 2,3-dihydroquinolin-4-ones
Rajput, Santosh,Gardner, Christopher R.,Failes, Timothy W.,Arndt, Greg M.,Black, David Stc.,Kumar, Naresh
, p. 105 - 115 (2014/01/17)
A series of 3-aryl-5,7-dimethoxyquinolin-4-ones 8 and 3-aryl-5,7-dimethoxy- 2,3-dihydroquinolin-4-ones 13 were synthesized in good yields. Demethylation under a range of conditions afforded the corresponding 5-hydroxy and 5,7-dihydroxy derivatives. Biolog
Synthesis of 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-2- or 4-ones and derivatives
Croisy, Martine,Huel, Christiane,Bisagni, Emile
, p. 683 - 690 (2007/10/03)
Condensation of ethyl 2-(4-methoxyphenyl)-3-hydroxyacrylate with 3,5-dimethoxyaniline afforded, depending on experimental conditions, either 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-2-one or 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-4-one. Whereas chlorination with phosphorous oxychloride led to the corresponding 2- and 4- chloroquinolines derivatives, 2-chloro-3-(4-methoxyphenyl)-5,7-dimethoxyquinoline was also obtained by using the Meth Cohn method's.
