190791-28-7

Usage

Uses

Used in Pharmaceutical Industry:
(4S,4'S)2,2'-(1-ethylpropylidene)bis[4,5-dihydro-4-phenyl-Oxazole is used as a potential intermediate in organic synthesis and medicinal chemistry for the development of new drugs and biologically active molecules. Its unique stereochemistry and functional groups make it a valuable candidate for creating innovative pharmaceutical compounds.

Upstream product

• 77-25-8 diethyl diethylmalonate 
• 510-20-3 diethyl malonic acid 
• 54505-72-5 diethylmalonyl chloride 
• 195515-46-9 N,N'-Bis[(1R)-2-chloro-1-phenylethyl]-2,2-diethyl-1,3-propanediamide 

Relevant academic research and scientific papers

Copper(II)-catalyzed enantioselective intramolecular cyclization of N-alkenylureas

The first Cu(II)-catalyzed highly enantioselective intramolecular cyclization of N-alkenylureas was developed for the concise assembly of chiral vicinal diamino bicyclic heterocycles. Facile removal of carbonyl group of the carbamido moiety allowed for ready access to enantioenriched cyclic vicinal diamines.

Enantioselective catalytic Diels-Alder reaction of ethyl 2-benzoylacrylate with chiral bis(oxazoline)- or mono(oxazoline)-magnesium complex

The magnesium catalysed Diels-Alder reaction of 2-benzoylacrylate gave the endo-adduct enantioselectively with bis(oxazoline) 5 as a C2-symmetric ligand or mono-(oxazoline) 4 as a non-C2-symmetric ligand.