54505-72-5

Basic information

• Product Name: DIETHYLMALONIC ACID DICHLORIDE
• Synonyms: 2,2-diethylMalonyl dichloride;Diethylmalonyl dichloride 98%;DIETHYLMALONIC ACID DICHLORIDE;DIETHYLMALONYL DICHLORIDE
• CAS NO: 54505-72-5
• Molecular Formula: C₇H₁₀Cl₂O₂
• Molecular Weight: 197.06
• Mol File: 54505-72-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 197-199 °C(lit.)
• Flash Point: 165 °F
• Appearance: /
• Density: 1.145 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.368mmHg at 25°C
• Refractive Index: n20/D 1.459(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: DIETHYLMALONIC ACID DICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLMALONIC ACID DICHLORIDE(54505-72-5)
• EPA Substance Registry System: DIETHYLMALONIC ACID DICHLORIDE(54505-72-5)

Safety Data

• Hazard Codes: C
• Statements: 34-36/37
• Safety Statements: 23-26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 54505-72-5(Hazardous Substances Data)

Usage

Uses

Diethylmalonyl dichloride has been used in the preparation of:5,5-diethyl-1,3-dihydroxybarbituric acid (N,N′-dihydroxyveronal) via condensation with 1,3-dibenzyloxyurea1,11-dibronzo-4,8-diaza-6,6-diethyl-5,7-dioxoundecaneamide containing crowned derivatives of dithiomaleonitrile

InChI:InChI=1/C7H10Cl2O2/c1-3-7(4-2,5(8)10)6(9)11/h3-4H2,1-2H3

Upstream product

• 510-20-3 diethyl malonic acid 
• 77-25-8 diethyl diethylmalonate 
• 2736-40-5 chlorure d'acide ethyl-2 butyrique 
• 503-38-8 trichloromethyl chloroformate 
• 57-44-3 diethylbarbituric acid 

Downstream Products

• 92108-24-2 3,3-Diethyl-1-(phenylamino)-2,4-azetidindion 
• 1732-61-2 1-phenyl-4,4-diethyl-3,5-pyrazolidinedione 
• 29264-10-6 diethyl-malonic acid bis-(N'-phenyl-hydrazide) 
• 64289-52-7 acide diethyl-5,5 imino-2 barbiturique 
• 64289-52-7 2-amino-5,5-diethyl-1H-pyrimidine-4,6-dione 
• 101496-40-6 3,3-diethyl-1-(4-dimethylamino-phenyl)-azetidine-2,4-dione 
• 15745-94-5 3,3-diethyl-1-phenyl-azetidine-2,4-dione 
• 58655-60-0 diethyl-malonic acid-dianilide 
• 57-44-3 diethylbarbituric acid 
• 63884-60-6 N,N'-bis-ethoxycarbonyl-2,2-diethyl-malonic acid diamide 
• 500336-55-0 5,5-diethyl-2,4,6-trioxo-tetrahydro-pyrimidine-1-carboxylic acid ethyl ester 
• 56945-80-3 3-cyclohexyl-6,6-diethyl-pyrazolo[5,1-b][1,3]oxazine-2,5,7-trione 
• 88-09-5 2-Ethylbutanoic acid 
• 6832-96-8 2-ethyl-N-phenylbutanamide 

Relevant articles and documents

Copper(II)-catalyzed enantioselective intramolecular cyclization of N-alkenylureas

The first Cu(II)-catalyzed highly enantioselective intramolecular cyclization of N-alkenylureas was developed for the concise assembly of chiral vicinal diamino bicyclic heterocycles. Facile removal of carbonyl group of the carbamido moiety allowed for ready access to enantioenriched cyclic vicinal diamines.

Highly enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated ketones with simple Cu(II)-oxazoline-imidazoline catalysts

A series of novel chiral ligands L1-L4 with an imidazoline-oxazoline framework have been developed as new type of non-symmetric N,N-bidentate ligands. All the chiral ligands were prepared from 2,2-diethylmalonic acid and enantiomerically pure (S)-2-amino-