190961-74-1

Basic information

• Product Name: Ethanone, 1-[(2R,3S)-3-phenyloxiranyl]- (9CI)
• Synonyms: Ethanone, 1-[(2R,3S)-3-phenyloxiranyl]- (9CI)
• CAS NO: 190961-74-1
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.1852
• Product Categories: ACETYLGROUP
• Mol File: 190961-74-1.mol
• Article Data: 34

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-[(2R,3S)-3-phenyloxiranyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[(2R,3S)-3-phenyloxiranyl]- (9CI)(190961-74-1)
• EPA Substance Registry System: Ethanone, 1-[(2R,3S)-3-phenyloxiranyl]- (9CI)(190961-74-1)

Safety Data

• Hazardous Substances Data: 190961-74-1(Hazardous Substances Data)

Upstream product

• 852609-74-6 3-chloro-4-hydroxy-4-phenylbutan-2-one 
• 100-52-7 benzaldehyde 
• 67-64-1 acetone 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 17488-65-2 4-phenylbut-3-en-2-ol 
• 246236-69-1 (E)-1-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-3-phenyl-propenone 
• 102-92-1 Cinnamoyl chloride 
• 78-95-5 chloroacetone 
• 917-54-4 methyllithium 
• 681121-99-3 (2R,3S)-3-Phenyl-oxirane-2-carboxylic acid diphenylamide 
• 1896-62-4 (E)-benzalacetone 
• 246236-71-5 ((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-((2R,3S)-3-phenyl-oxiranyl)-methanone 

Downstream Products

• 190912-78-8 (-)-(1S,2R,3S)-1,3-Diphenyl-1,2-epoxybutan-3-ol 

Relevant articles and documents

Asymmetric Cascade Catalysis with Chiral Polyoxometalate-Based Frameworks: Sequential Direct Aldol and Epoxidation Reactions

Catalytic asymmetric cascade reactions in which the substrates are transferred through well-choreographed consecutive independent steps by a single catalyst have received increasing interest. By incorporating a chiral organocatalyst pyrrolidine, an oxidat

Switchable asymmetric bio-epoxidation of α,β-unsaturated ketones

Efficient asymmetric bio-epoxidation of electron-deficient α,β-unsaturated ketones was realized via a tandem reduction-epoxidation-dehydrogenation cascade, which proceeds in a switchable manner to afford either chiral epoxy ketones or allylic epoxy alcoho

A highly enantioselective synthesis of the odorant, 3-hydroxy-4- phenylbutan-2-one

An efficient and highly enantioselective synthesis of 3-hydroxy-4- phenylbutan-2-one was developed involving the asymmetric epoxidation of an enone and hydrogenolysis of an α,β-epoxyketone. 1-Phenyl-3-buten-2-one was epoxidised with t-butyl hydroperoxide using a chiral La-BINOL-Ph3P=O complex as the catalyst to give (3S,4R)- or (3R,4S)- 3,4-epoxy-4-phenylbutan-2- one in ～90% yield and 97% ee. The resultant optically active epoxyketone was reduced in the presence of Pd/C (5 mol%) and H2 (3 bar) in THF at room temperature to produce (S)- or (R)-3-hydroxy-4-phenylbutan- 2-one in ～80% yield with more than 90% enantiomeric excess.