681121-99-3Relevant academic research and scientific papers
Phase-transfer-catalyzed asymmetric Darzens reaction using a new chiral ammonium salt
Arai, Shigeru,Tokumaru, Kazuyuki,Aoyama, Toyohiko
, p. 1845 - 1848 (2004)
Catalytic asymmetric Darzens reaction of haloamides is described. A new and easily-prepared bis-ammonium salt derived from BINOL acts as an effective phase-transfer catalyst and efficiently promotes the reaction to give the desired epoxides under quite mild conditions with up to 70% ee.
