19155-54-5Relevant academic research and scientific papers
2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY
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Page/Page column 75, (2016/09/22)
A compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.
Quaternary ammonium N,N-dichloroamines as topical, antimicrobial agents
Francavilla, Charles,Low, Eddy,Nair, Satheesh,Kim, Bum,Shiau, Timothy P.,Debabov, Dmitri,Celeri, Chris,Alvarez, Nichole,Houchin, Ashley,Xu, Ping,Najafi, Ron,Jain, Rakesh
scheme or table, p. 2731 - 2734 (2010/03/03)
A series of backbone modified and sulfonic acid replacement analogs of our topical, clinical candidate (iii) were synthesized. Their antimicrobial activities and aqueous stabilities at pH 4 and pH 7 were determined, and has led us to identify quaternary ammonium N,N-dichloroamines as a new class of topical antimicrobial agents.
