192197-34-5

Basic information

• Product Name: Pyrimidine, 2-(1-pyrrolidinyl)- (9CI)
• Synonyms: Pyrimidine, 2-(1-pyrrolidinyl)- (9CI)
• CAS NO: 192197-34-5
• Molecular Formula: C8H11N3
• Molecular Weight: 149.19304
• Product Categories: PYRIMIDINE
• Mol File: 192197-34-5.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Pyrimidine, 2-(1-pyrrolidinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 2-(1-pyrrolidinyl)- (9CI)(192197-34-5)
• EPA Substance Registry System: Pyrimidine, 2-(1-pyrrolidinyl)- (9CI)(192197-34-5)

Safety Data

• Hazardous Substances Data: 192197-34-5(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 14080-23-0 2-cyanopyrimidine 
• 4595-60-2 2-bromopyrimidine 
• 1722-12-9 2-chloropyrimidine 
• 114646-17-2 2-pyrrol-1-yl-pyrimidine 

Downstream Products

• 1015242-07-5 2-(pyrrolidin-1-yl)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrimidine 

Relevant articles and documents

Synthesis of tetrahydropyrimidinium salts and their in situ catalytic activities towards the Buchwald-Hartwig amination reaction under microwave irradiation

A series of asymmetrical substituted tetrahydropyrimidinium salts and different kinds of bridged bistetrahydropyrimidinium salts were prepared through the quaterization of tetrahydropyrimidine or the dehydrogenation of hexahydropyrimidine. They were chara

Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive

An efficient and operationally simple Ni-catalyzed amination protocol has been developed. This methodology features a simple NiII salt, an organic base and catalytic amounts of both a pyridinium additive and Zn metal. A diverse number of (hetero)aryl halides were coupled successfully with primary and secondary alkyl amines, and anilines in good to excellent yields. Similarly, benzophenone imine gave the corresponding N-arylation product in an excellent yield.

Cu(II)-catalyzed C-N coupling of (hetero)aryl halides and N-Nucleophiles promoted by α-benzoin oxime

We first reported the new application of a translate metal chelating ligand α-benzoin oxime for improving Cu-catalyzed C-N coupling reactions. The system could catalyse coupling reactions of (hetero)aryl halides with a wide of nucleophiles (e.g., azoles, piperidine, pyrrolidine and amino acids) in moderate to excellent yields. The protocol allows rapid access to the most common scaαolds found in FDA-approved pharmaceuticals.

Decyanative Cross-Coupling of Cyanopyrimidines with O-, S-, and N-Nucleophiles: A Route to Alkoxylpyrimidines, Aminopyrimidines and Alkylthiopyrimidines

The transition metal-free cross-coupling reactions of cyanopyrimidines with aliphatic alcohols, thiols (or S-alkylisothiourea salts) and amines, giving the corresponding alkoxylpyrimidines, aminopyrimidines, and alkylthiopyrimidines, are reported. Prelimi