192370-83-5

Upstream product

• 192370-74-4 (5S,6S,7S)-10-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-4,4,6-trimethyl-3-oxo-decanoic acid tert-butyl ester 
• 219824-47-2 (3S,4S)-7-(benzyloxy)-3-methylhept-1-en-4-ol 
• 192370-73-3 (2R,3S)-6-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylhexanal 
• 192370-72-2 [(1S,2S)-1-(3-Benzyloxy-propyl)-2-methyl-but-3-enyloxy]-tert-butyl-dimethyl-silane 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 5470-84-8 4-benzyloxybutanal 
• 192370-75-5 (3S,5S,6S,7S)-10-Benzyloxy-3,7-bis-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-4,4,6-trimethyl-decanoic acid tert-butyl ester 

Relevant academic research and scientific papers

Stereoselective syntheses and evaluation of compounds in the 8-desmethylepothilone a series: Some surprising observations regarding their chemical and biological properties

The title compounds have been synthesized in a convergent way by recourse to a Weiler type dianion construction.