1928-77-4

Basic information

• Product Name: 6-CHLORO-7-BENZYLPURINE
• Synonyms: 6-CHLORO-7-BENZYLPURINE;7-BENZYL-6-CHLORO-7H-PURINE;7-BENZYL-6-CHLOROPURINE;7-BENYL-6-CHLORO-9H-PURINE;6-CHLORO-7-(PHENYLMETHYL)-7H-PURINE;6-chloro-7-(phenylmethyl)purine;NSC 25717
• CAS NO: 1928-77-4
• Molecular Formula: C₁₂H₉ClN₄
• Molecular Weight: 244.68
• Product Categories: Heterocyclic Compounds;Bases & Related Reagents;Heterocycles;Nucleotides
• Mol File: 1928-77-4.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 441 °C at 760 mmHg
• Flash Point: 220.5 °C
• Appearance: white solid
• Density: 1.4 g/cm³
• Vapor Pressure: 5.64E-08mmHg at 25°C
• Refractive Index: 1.706
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 6-CHLORO-7-BENZYLPURINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-7-BENZYLPURINE(1928-77-4)
• EPA Substance Registry System: 6-CHLORO-7-BENZYLPURINE(1928-77-4)

Safety Data

• Hazardous Substances Data: 1928-77-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 1928-77-4 differently. You can refer to the following data:
1. A useful intermediate in the synthesis of 1-substituted adenines
2. A useful intermediate in the synthesis of 1-substituted adenines.

InChI:InChI=1/C12H9ClN4/c13-11-10-12(15-7-14-11)16-8-17(10)6-9-4-2-1-3-5-9/h1-5,7-8H,6H2

Upstream product

• 3724-43-4 Vilsmeier reagent 
• 100-44-7 benzyl chloride 
• 87-42-3 6-chloro-7H-purine 
• 1374867-86-3 9-tert-butoxycarbonyl-7-benzyl-6-chloro-7,8-dihydropurine 
• 1374867-77-2 9-tert-butoxycarbonyl-6-chloro-7,8-dihydropurine 
• 851165-38-3 9-tert-butoxycarbonyl-6-chloro-9H-purine 
• 87-42-3 6-chloropurine 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 1258274-72-4 6-chloro-7,8-dihydro-9-tritylpurine 
• 1008361-76-9 6-chloro-9-trityl-9H-purine 

Downstream Products

• 1246307-16-3 8-bromo-6-chloro-7-(phenylmethyl)-7H-purine 
• 3691-50-7 7-benzyladenine 
• 1431332-82-9 7-benzyl-N-(triphenylphosphoranylidene)purine-6-amine 
• 1491884-91-3 7,9-dibenzyl-6-chloro-8-oxo-7,8-dihydro-9H-purine 

Relevant articles and documents

Regioselective alkylation reaction of purines under microwave irradiation

The alkylation of purines which is generally carried out after anion formation by treatment with a base and alkyl halide is complicated and in the best cases, mixtures of N-alkylated compounds are obtained. Purine derivatives can be acquired from alkylati

METHOD FOR SYNTHESIZING DIVERSELY SUBSTITUTED PURINES

The present invention relates to a method for synthesizing diversely substituted purines starting from a pyrimidine. Formula (I). The method comprises the formation of an amidine group on the pyrimidine by implementing a Vilsmeier type reagent, the functi

Direct, Regioselective N-Alkylation of 1,3-Azoles

Regioselective N-alkylation of 1,3-azoles is a valuable transformation. Organomagnesium reagents were discovered to be competent bases to affect regioselective alkylation of various 1,3-azoles. Counterintuitively, substitution selectively occurred at the more sterically hindered nitrogen atom. Numerous examples are provided, on varying 1,3-azole scaffolds, with yields ranging from 25 to 95%.