192803-36-4

Upstream product

• 100-44-7 benzyl chloride 
• 50-00-0 formaldehyd 
• 3421-95-2 4-(benzyloxy)-2-(tert-butyl)phenol 
• 1948-33-0 tert-butylhydroquinone 

Downstream Products

• 805314-84-5 (4-methoxy-phenoxy)-acetic acid 3-tert-butyl-5-formyl-4-hydroxy-phenyl ester 
• 616873-79-1 1,3,5-benzenetrioxytriacetic acid tri-(3-tert-butyl-5-formyl-4-hydroxy-phenyl)ester 
• 616873-78-0 p-phenylenedioxydiacetic acid di-(3-tert-butyl-5-formyl-4-hydroxy-phenyl)ester 
• 192803-37-5 3-tert-butyl-2,5-dihydroxybenzaldehyde 

Relevant academic research and scientific papers

Polymeric salen-Ti(IV) or V(V) complex catalyzed asymmetric synthesis of O-acetylcyanohydrins from KCN, Ac2O and aldehydes

Polymeric salen-Ti(IV) and V(V) complexes were employed in the enantioselective O-acetyl cyanation of aldehydes with potassium cyanide and acetic anhydride. The crosslinked polymeric salen-Ti(IV) catalyst exhibited good activities and enantioselectivities, up to 91% ee with 99% conversion was obtained at -20°C with 1 mol% of catalyst (based on bimetallic catalytic unit). Moreover, six consecutive recyclings with the easily recovered crosslinked polymeric catalyst showed no obvious decrease in either activity or enantioselectivity. Linear polymeric salen-V(V) catalyst showed good catalytic efficiency too, up to 94% ee with 99% conversion was obtained at -42°C with 5 mol% of catalyst. Graphical Abstract.

Highly enantioselective resolution of terminal epoxides with cross-linked polymeric salen-Co(III) complexes

Crosslinked polymeric salen-Co(III) complexes derived from a novel dialdehyde and a trialdehyde were synthesized and employed in the hydrolytic kinetic resolution (HKR) of terminal epoxides. Up to 99% ee were obtained with only 0.16-0.02 mol% of catalyst (based on catalytic unit).