192929-33-2Relevant academic research and scientific papers
Antiproliferation and apoptosis induced by C-glycosides in human leukemia cancer cells
Sanhueza, Carlos A.,Mayato, Carlos,Garcia-Chicano, Maria,Diaz-Penate, Raquel,Dorta, Rosa L.,Vazquez, Jesus T.
, p. 4223 - 4227 (2007/10/03)
A large series of alkyl C-glycosides was synthesized from d-glucal or d-galactal. These compounds were screened against the human promyelocytic leukemia cell line (HL60), showing significant activity and apoptosis. Up to 13 C-glucopyranosides, but no C-ga
Stereoselective synthesis of allyl-C-mannosyl compounds: Use of a temporary silicon connection in intramolecular allylation strategies with allylsilanes
Beignet, Julien,Tiernan, James,Woo, Chang H.,Kariuki, Benson M.,Cox, Liam R.
, p. 6341 - 6356 (2007/10/03)
Methyl mannoside 16 containing an allyldimethylsilyl ether at C(2) was synthesized in nine steps from D-mannose. Reaction with TMSOTf in MeCN at room-temperature effected C-glycosylation to provide the α-allyl-C- mannosyl product 18 with excellent stereos
