193287-50-2

Upstream product

• 79-04-9 chloroacetyl chloride 
• 193287-46-6 methyl 6-amino-2,3-di-O-benzyl-6-deoxy-4-O-methyl-α-D-glucopyranoside 
• 17791-36-5 methyl 2,3-di-O-benzyl-α-D-glucopyranoside 
• 193287-44-4 methyl 6-azido-2,3-di-O-benzyl-6-deoxy-4-O-methyl-α-D-glucopyranoside 
• 193287-42-2 methyl 2,3-di-O-benzyl-6-chloro-6-deoxy-4-O-methyl-α-D-glucopyranoside 
• 67776-12-9 methyl 2,3-di-O-benzyl-6-chloro-6-deoxy-α-D-glucopyranoside 

Downstream Products

• 193287-51-3 methyl 2,3-di-O-benzyl-6-{[N,N-bis-(benzyloxycarbonylmethyl)-amino]-acetamido}-6-deoxy-4-O-methyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of novel amino acid glycoside conjugates

A new class of non-anomeric amino acid glycoconjugates can be prepared starting from either ω-amino- or ω-halodeoxyglucosides. Treatment of an ether-protected methyl 7-amino-6,7-dideoxy-α-D-glucoheptopyranoside with methyl aspartate isocyanate gave an urea-linked conjugate of methyl glucoheptopyranoside and aspartic acid. Nucleophilic displacement of the ether-protected methyl 6-chloro-6-deoxy-α-D-glucopyranoside with potassium succinimide followed by imide ring opening and amidation of the succinic acid monoamide with dimethyl iminodiacetate led to a conjugate of methyl 6-amino-6-deoxy-α-D-glucopyranoside and iminoodiacetate bridged by succinate.