19340-91-1Relevant academic research and scientific papers
Superparamagnetic iron oxide as an efficient catalyst for the one-pot, solvent-free synthesis of α-aminonitriles
Mojtahedi, Mohammad M.,Saeed Abaee,Alishiri, Tooba
experimental part, p. 2322 - 2325 (2009/09/06)
Superparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of α-aminonitriles from aldehydes, amines, and TMSCN. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeable loss of activity. The products are obtained rapidly at room temperature in good purity upon separation of the catalyst and evaporation of the volatiles of the reaction mixture.
One-pot, solvent-free synthesis of α-aminonitriles under catalysis by magnesium bromide ethyl etherate
Mojtahedi, Mohammad M.,Abaee, M. Saeed,Abbasi, Hasean
, p. 429 - 432 (2007/10/03)
A three-component, efficient, and facile procedure has been developed for the synthesis of α-aminonitriles from aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of magnesium bromide ethyl etherate in the absence of solvent. Rapid formation of products is observed at room temperature in a one-pot procedure under very mild conditions giving excellent yields of the title compounds.
Lithium perchlorate/diethylether catalyzed aminocyanation of aldehydes
Heydari, Akbar,Fatemi, Parinaz,Alizadeh, Abdol-Ali
, p. 3049 - 3050 (2007/10/03)
A simple and efficient one-pot method was developed to give α- aminonitriles from aldehydes + amines + TMSCN in LPDE. Optically active α- aminonitriles were snythesized by using (S)-(-)- or (R) (+) α- methylbenzylamine, (S)-(-) α-methylbenzylamine affords
