193738-18-0

Upstream product

• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 3392-97-0 2,6-dimethoxybenzaldehyde 

Downstream Products

• 1026585-41-0 [3-Hydroxy-2-(2,2,2-trifluoro-acetyl)-phenoxy]-acetic acid methyl ester 
• 193738-66-8 2,2,2-Trifluoro-1-(2-hydroxy-6-methoxy-phenyl)-ethanone 
• 70211-42-6 1-(2,6-dihydroxyphenyl)trifluoromethylketone 
• 190665-12-4 1-(2,6-dimethoxyphenyl)trifluoromethylketone 

Relevant academic research and scientific papers

Benzofuran derivatives as ET(A)-selective, non-peptide endothelin antagonists

The synthesis and SAR relationships of a series of 4-benzyloxy-3-methylbenzofuran-2-carboxylic acids are described. Compounds from this series show 2- to 16-fold selective binding to the ET(A) receptor in the micromolar range, and two compounds from this series (32 and 40) were demonstrated to exhibit ET(A) antagonist activity.

1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS

Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula:A typical example for a compound according to above formula is: A typical example for a compound according to above formula is: