194044-54-7

Basic information

• Product Name: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonami de
• Synonyms: 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide;Ccris 9330;Hsdb 7038;p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
• CAS NO: 194044-54-7
• Molecular Formula: C17H14F3N3O2S
• Molecular Weight: 0
• Mol File: 194044-54-7.mol
• Article Data: 125

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonami de(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonami de(194044-54-7)
• EPA Substance Registry System: 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonami de(194044-54-7)

Safety Data

• Hazardous Substances Data: 194044-54-7(Hazardous Substances Data)

Upstream product

• 929030-65-9 N-[bis(4-methoxyphenyl)phenylmethyl]-4-[3-(bromodifluoromethyl)-5-p-tolylpyrazol-1-yl]-benzenesulfonamide 
• 383-63-1 ethyl trifluoroacetate, 
• 17852-52-7 4-hydrazinobenzene-1-sulfonamide hydrochloride 
• 122-00-9 para-methylacetophenone 
• 720-94-5 4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione 
• 4392-54-5 4-aminosulfonylphenylhydrazine 
• 365530-13-8 4-[5-(4-methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]aniline 
• 100-16-3 4-nitrophenylhydrazone 
• 365530-10-5 5-(4-methylphenyl)-1-(4-nitrophenyl)-3-trifluoromethylpyrazole 
• 928658-43-9 1-(4'-methylphenyl)-4,4,4-trifluorobut-2-yn-1-ol 
• 701-34-8 4-bromo-benzenesulfonic acid amide 
• 232947-12-5 1,1,1-trifluoro-4-(4’-tolyl)but-3-en-2-one 
• 402-46-0 4-fluorophenylsulphonamide 
• 26974-15-2 5-(4-methylbenzene)-3-(trifluoromethyl)-1H-pyrazole 

Downstream Products

• 1426535-47-8 C₂₆H₂₂F₃N₃O₃S 
• 1426535-45-6 C₂₆H₂₁F₃N₄O₅S 
• 1426535-43-4 C₂₅H₁₉F₃N₄O₅S 

Relevant articles and documents

Application of (MWCNTs)-COOH/CeO2 hybrid as an efficient catalyst for the synthesis of some nitrogen-containing organic compounds

ABSTRACT: Modification of acid functionalized multi-walled carbon nanotubes (MWCNTs)-COOH with CeO2 nanoparticles using Ce(NO3)2.6H2O, produced an efficient catalyst for the synthesis of some nitrogen-containing heterocycles such as celecoxib. The products were identified by CHN analysis, NMR, and FT-IR spectra. On the other hand, synthesis of CeO2 nanoparticles and their conjugation on the surface of (MWCNTs)-COOH have been confirmed by FT-IR, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and Energy-dispersive X-ray spectroscopy (EDX).

Rapid Access to N-Protected Sulfonimidoyl Fluorides: Divergent Synthesis of Sulfonamides and Sulfonimidamides

Herein we report a practical and efficient copper-catalyzed approach for the conversion of various arenediazonium salts to the corresponding N-protected sulfonimidoyl fluorides. This operationally simple protocol tolerates a wide range of functional groups and can be applied to the late-stage modification of complex bioactive molecules. Furthermore, pharmaceutically important primary sulfonamides and sulfonimidamides derived from these valuable N-protected sulfonimidoyl fluoride units were prepared in minimal synthetic steps.

A CONTINUOUS FLOW MICRO-TOTAL PROCESS SYSTEM FOR PREPARATION OF CELECOXIB AND ANALOGS THEREOF

The present invention relates to preparation of pyrazoles. This invention further relates to a continuous flow micro-total process system for preparation of celecoxib, a COX-2 selective non-steroidal anti-inflammatory drug, and analogs thereof.