195304-45-1Relevant articles and documents
Structurally simplified zaragozic acid (squalestatin): Stereoselective preparation of a 3,4-unsubstituted derivative
Ito, Hisanaka,Matsumoto, Miyoko,Yoshizawa, Takeshi,Takao, Ken-Ichi,Kobayashi, Susumu
, p. 9009 - 9012 (2007/10/03)
Stereoselective preparation of a structurally simplified 3,4-unsubstituted zaragozic acid derivative was achieved starting from D-glucose. The present approach involved the stereoselective addition of a vinyl Grignard reagent, selective cleavage of 1,2-diol, and regioselective acylation of the hydroxyl group at C-6.