195304-46-2

Basic information

• Product Name: {(2S,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propoxy}-tert-butyl-dimethyl-silane
• Synonyms: {(2S,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propoxy}-tert-butyl-dimethyl-silane
• CAS NO: 195304-46-2
• Molecular Weight: 741.053
• Mol File: 195304-46-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(2S,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propoxy}-tert-butyl-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: {(2S,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propoxy}-tert-butyl-dimethyl-silane(195304-46-2)
• EPA Substance Registry System: {(2S,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propoxy}-tert-butyl-dimethyl-silane(195304-46-2)

Safety Data

• Hazardous Substances Data: 195304-46-2(Hazardous Substances Data)

Upstream product

• 195304-44-0 (3R,4R,5S)-4,5-Bis-benzyloxy-3-((R)-1,2-bis-benzyloxy-ethyl)-6-(tert-butyl-dimethyl-silanyloxy)-hex-1-en-3-ol 
• 195304-43-9 (2R,4R,5S)-1,2,4,5-Tetrakis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-hexan-3-one 
• 195304-42-8 (2R,3R,4S,5S)-1,2,4,5-Tetrakis-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-hexan-3-ol 
• 201603-51-2 methyl 2,3,5,6-tetra-O-benzylglucofuranoside 
• 195304-41-7 (2S,3S,4R,5R)-2,3,5,6-Tetrakis-benzyloxy-hexane-1,4-diol 
• 89539-39-9 2,3,5,6-tetra-O-benzyl-D-glucofuranose 
• 55902-93-7 methyl 3,5,6-tri-O-benzyl-α,β-D-glucofuranoside 
• 100-39-0 benzyl bromide 
• 77-76-9 2,2-dimethoxy-propane 
• 195304-45-1 (3R,4R,5S)-4,5-Bis-benzyloxy-3-((R)-1,2-bis-benzyloxy-ethyl)-6-(tert-butyl-dimethyl-silanyloxy)-hexane-1,3-diol 

Downstream Products

• 195304-54-2 (1S,5S,6R,7R)-6,7-Dihydroxy-1-(6-phenyl-hexyl)-2,8-dioxa-bicyclo[3.2.1]octane-5-carbaldehyde 
• 195304-53-1 (1S,5R,6R,7R)-5-((R)-1,2-Dihydroxy-ethyl)-1-(6-phenyl-hexyl)-2,8-dioxa-bicyclo[3.2.1]octane-6,7-diol 
• 195304-55-3 (1S,5S,6R,7R)-6,7-Dihydroxy-1-(6-phenyl-hexyl)-2,8-dioxa-bicyclo[3.2.1]octane-5-carboxylic acid 
• 195304-48-4 (2R,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propionaldehyde 
• 195304-52-0 (1S,5R,6R,7R)-6,7-Bis-benzyloxy-5-((R)-1,2-bis-benzyloxy-ethyl)-1-(6-phenyl-hexyl)-2,8-dioxa-bicyclo[3.2.1]octane 
• 195304-51-9 (1R,2R)-1,2-Bis-benzyloxy-1-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-9-phenyl-nonan-3-one 
• 195304-47-3 (2S,3R)-2,3-Bis-benzyloxy-3-[(R)-4-((R)-1,2-bis-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-propan-1-ol 

Relevant articles and documents

Structurally simplified zaragozic acid (squalestatin): Stereoselective preparation of a 3,4-unsubstituted derivative

Stereoselective preparation of a structurally simplified 3,4-unsubstituted zaragozic acid derivative was achieved starting from D-glucose. The present approach involved the stereoselective addition of a vinyl Grignard reagent, selective cleavage of 1,2-diol, and regioselective acylation of the hydroxyl group at C-6.