19532-73-1Relevant academic research and scientific papers
1H, 13C, 15N, 2D and Variable Temperature NMR Study of the Role of Hydrogen Bonding in the Structure and Conformation of Oxamide Derivatives
Martinez-Martinez, Francisco Javier,Ariza-Castolo, Armando,Tlahuext, Hugo,Tlahuextl, Margarita,Contreras, Rosalinda
, p. 1481 - 1485 (2007/10/02)
The structure and conformation of N,N'-bisoxamide (1); N,N'-bisoxamide (2); N,N'-bis(phenyl)oxamide (3); N,N'-bisoxamide (4); N,N'-bisoxamide (5); N-methylamide (6); N-methylamide (7); N-phenylmethylamide (8); N-methylamide (9) and N-methylamide (10) were unambiguously established by 1H, 13C, 15N, 2D and variable temperature NMR spectroscopy.A careful NMR investigation of the conformational behaviour in these systems was relevant.It has been found that the dicarbonylic group in compounds 1-5 has a trans geometry, stabilized by intramolecular hydrogen bonding and that they possess a C2 axis.Compounds 1 and 2 are planar and compounds 1, 2, 4 and 5 present the amidic proton coordinated by two oxygen atoms.
Efficient Synthesis of Benzo-Substituted Macrocyclic Diamides
Ibrahim, Yehia A.,Elwahy, Ahmed H. M.
, p. 1684 - 1696 (2007/10/02)
A series of new 13-16-membered macrocyclic dibenzo- and tribenzodioxadiamides and trioxadiamides (macrooxacyclams) 3-9, 11-13 has been prepared.Good to excellent yields (32-87percent) were achieved in the macrocyclization step by reacting the dipotassium
