19542-44-0 Usage
Description
Z-D-ALA-PHE-OH, also known as Z-D-Ala-Phe-OH or Z-D-alanylphenylalanine, is a synthetic compound composed of the amino acids D-alanine and phenylalanine linked by a peptide bond. It is recognized for its stability and structural similarity to naturally occurring peptides, making it a valuable model peptide in research studies. Z-D-ALA-PHE-OH demonstrates a range of biological activities, such as antimicrobial properties and the ability to inhibit enzymes like proteases. Additionally, it serves as a building block in the synthesis of peptidomimetic compounds, which have potential therapeutic applications in drug discovery. Z-D-ALA-PHE-OH holds a significant position in peptide chemistry and is instrumental in the advancement of novel pharmaceutical agents.
Uses
Used in Pharmaceutical Research:
Z-D-ALA-PHE-OH is used as a model peptide for [research studies] because of [its stability and structural resemblance to naturally occurring peptides].
Used in Antimicrobial Applications:
Z-D-ALA-PHE-OH is used as an antimicrobial agent for [its ability to exhibit antimicrobial properties].
Used in Enzyme Inhibition:
Z-D-ALA-PHE-OH is used as an enzyme inhibitor for [its capacity to inhibit enzymes such as proteases].
Used in Drug Discovery:
Z-D-ALA-PHE-OH is used as a building block for the synthesis of peptidomimetic compounds for [potential therapeutic applications in drug discovery].
Used in Peptide Chemistry:
Z-D-ALA-PHE-OH is used in peptide chemistry for [contributing to the development of novel pharmaceutical agents].
Check Digit Verification of cas no
The CAS Registry Mumber 19542-44-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,5,4 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19542-44:
(7*1)+(6*9)+(5*5)+(4*4)+(3*2)+(2*4)+(1*4)=120
120 % 10 = 0
So 19542-44-0 is a valid CAS Registry Number.
19542-44-0Relevant articles and documents
A modular approach to cyclic tetrapeptides related to histone deacetylase inhibition: Synthesis of epi-microsporin A
Mukherjee, Jyoti Prasad,Sil, Suman,Chattopadhyay, Shital K.
, p. 739 - 742 (2016)
A short new route to the unusual amino acid component (S)-2-amino-8-oxodecanoic acid (Aoda) of some important HDAC inhibitors has been developed using cross metathesis reaction as the key step. An extension of the study employing grafting of a macrocyclic scaffold through cross metathesis has proved to be highly efficient for the synthesis of an isomer of the cyclic tetrapeptide HDAC inhibitor microsporin.
