195515-93-6Relevant articles and documents
Design, syntheses and potentiating activities against methicillin resistant Staphylococcus aureus of cyclic analogs of LY301621
Eid, Clark N.,Nicas, Thalia I.,Mullen, Deborah L.,Loncharich, Richard J.,Paschal, Jonathan W.
, p. 2087 - 2092 (1997)
Previous SAR studies of the diastereomers of LY301631 suggested the importance of a β-turn conformation for biological activity, In the present study, cyclic analogs were designed and synthesized that possess Type II and II' β-turns. Their biological activity will be discussed.