Bioorganic and Medicinal Chemistry Letters p. 2087 - 2092 (1997)
Update date:2022-09-26
Topics:
Eid, Clark N.
Nicas, Thalia I.
Mullen, Deborah L.
Loncharich, Richard J.
Paschal, Jonathan W.
Previous SAR studies of the diastereomers of LY301631 suggested the importance of a β-turn conformation for biological activity, In the present study, cyclic analogs were designed and synthesized that possess Type II and II' β-turns. Their biological activity will be discussed.
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