19578-72-4

Basic information

• Product Name: benzene, 2,4-dimethyl-1-(phenylmethoxy)-
• Synonyms: 1-(Benzyloxy)-2,4-dimethylbenzene; Benzyl 2,4-dimethylphenyl ether
• CAS NO: 19578-72-4
• Molecular Formula: C₁₅H₁₆O
• Molecular Weight: 212.2869
• Mol File: 19578-72-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 321.303°C at 760 mmHg
• Flash Point: 126.25°C
• Density: 1.027g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: benzene, 2,4-dimethyl-1-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: benzene, 2,4-dimethyl-1-(phenylmethoxy)-(19578-72-4)
• EPA Substance Registry System: benzene, 2,4-dimethyl-1-(phenylmethoxy)-(19578-72-4)

Safety Data

• Hazardous Substances Data: 19578-72-4(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 105-67-9 2,4-Xylenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 19578-84-8 2-benzyl-4,6-dimethylphenol 
• 102560-09-8 2,4,5,7-tetramethyl-9-phenyl-xanthene 
• 108-88-3 toluene 
• 105-67-9 2,4-Xylenol 
• 10366-16-2 4-methyl-2-phenethylphenol 

Relevant articles and documents

Metal-Free C-O Bond Functionalization: Catalytic Intramolecular and Intermolecular Benzylation of Arenes

A catalytic, metal-free intramolecular rearrangement of benzyl phenyl ethers using nitrosonium salt as a catalyst is described. The optimized reaction conditions enabled a catalytic and metal-free Friedel-Crafts alkylation reaction with benzylic alcohols, producing water as the stoichiometric byproduct. A comprehensive scope (>50 examples) for both approaches and application in drug synthesis were demonstrated. Mechanistic studies suggest a Lewis acid-based mechanism for the metal-free Friedel-Crafts reaction.