19610-34-5

Basic information

• Product Name: 1-(Hydroxymethyl)-o-carborane
• Synonyms: 1-(Hydroxymethyl)-o-carborane
• CAS NO: 19610-34-5
• Molecular Formula: C₃H₁₄B₁₀O
• Molecular Weight: 163.16
• Mol File: 19610-34-5.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Hydroxymethyl)-o-carborane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Hydroxymethyl)-o-carborane(19610-34-5)
• EPA Substance Registry System: 1-(Hydroxymethyl)-o-carborane(19610-34-5)

Safety Data

• Hazardous Substances Data: 19610-34-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 19528-60-0 1,2-C₂B₁₀H₁₁-1-CH₂OCOCH₃ 
• 50-00-0 formaldehyd 
• 16872-09-6 1,2-dicarba-closo-dodecaborane⁽¹²⁾ 
• 107-19-7 propargyl alcohol 
• 20394-07-4 1-formyl-o-carborane 
• 135457-09-9 (C₂B₁₀H₁₀(Si(CH₃)2C(CH₃)3))2(CH₂)4 
• 16853-85-3 lithium aluminium tetrahydride 
• 12072-09-2 1.2-C(CH₂OCOCF₃)CHB₁₀H₁₀ 
• 7732-18-5 water 
• 17702-41-9 nido-decaborane 
• 13861-22-8 prop-2-yn-1-yl methacrylate 
• 10477-47-1 propargyl acrylate 
• 7556-82-3 propargyl trifluoroacetate 

Downstream Products

• 17786-07-1 1-(CH₂Cl)-1,2-C₂HB₁₀H₁₀ 
• 83608-53-1 tris(o-carboranylmethyl) phosphate 
• 1373552-99-8 4-formylbenzoyloxymethylene-o-C-carborane 
• 253783-32-3 closo-[1-SPh-2-CH₂OH-1,2-C₂B₁₀H₁₀] 
• 16872-09-6 1,2-dicarba-closo-dodecaborane⁽¹²⁾ 
• 20394-07-4 1-formyl-o-carborane 
• 17526-10-2 1-benzyl-1,2-dicarba-closo-dodecaborane(11) 
• 117162-37-5 1-{(2,3,5-tri-O-benzoyl-D-ribofuranosyl)methyl}-1,2-dicarba-closo-dodecaborane 

Relevant articles and documents

Ortho-Carborane-Modified N-Substituted Deoxynojirimycins

N-alkyl-deoxynojirimycins (DNMs) are an important class of glycoprocessing enzyme inhibitors. Our work on DNMs focuses on identifying potent and selective inhibitors of the human enzymes, glucosylceramide synthase (GCS), lysosomal glucosylceramidase (GBA)

Hydroxyl carborane derivative containing ether bond, and modified curing agent, preparation method and application thereof

The invention discloses a hydroxyl carborane derivative containing an ether bond, a modified curing agent a preparation method and application of the hydroxyl carborane derivative. The structural formula of the hydroxyl carborane derivative containing the ether bond is one of the following formulas, wherein in the formula, an R1 group is -CH2CH2-, or an R3 group is -CH3, -CH2CH2CH3, -CH(CH3)2 and -CH2Ph. The preparation method comprises the following steps: carrying out hydroformylation on o-carborane to prepare o-carborane B-1 containing a single aldehyde group; carrying out reduction hydroxylation on the aldehyde group to prepare o-carborane B-2 containing a hydroxyl group; carrying out ring-opening reaction on the hydroxyl and epoxide to generate the hydroxyl carborane derivative containing the ether bond; and dropwise adding the derivative into an isocyanate curing agent for modification to obtain the modified curing agent. The finally obtained modified curing agent is longer in storage time, and an obtained paint film has the characteristics of high drying speed, strong flexibility and the like after the modified curing agent is mixed with resin.

Method for regulating and controlling structure of o-carborane derivative through preoccupation

The invention discloses a method for regulating and controlling the structure of an o-carborane derivative through preoccupation. The method comprises the following steps: (1) subjecting o-carborane to lithiation to form a monolithium salt and then reacting the monolithium salt with a CH group protecting agent so as to quantitatively convert the o-carborane into C-H protected carborane; (2) activating C-H by using butyllithium and then carrying out functionalization of a second carbon position; and (3) carrying out deprotection by using tetrabutyl ammonium fluoride. According to the invention, the CH group protecting agent is introduced at first, then the group is subjected to functionalization, and finally deprotection of the group is carried out, so the structure of the o-carborane derivative is regulated and controlled through preoccupation; and thus, a monosubstituted or disubstituted o-carborane derivative is purposefully and selectively synthesized. The obtained monosubstituted or disubstituted o-carborane derivative can be applied to field of aerospace materials like high-temperature-resistant bonding materials and composite materials and has great application prospect in the fields like biological medicines, catalysts, supramolecular systems and high energy fuels.