19615-30-6

Basic information

• Product Name: PIPERIDIN-2-YL-ACETIC ACID HYDROCHLORIDE
• Synonyms: PIPERIDIN-2-YL-ACETIC ACID HYDROCHLORIDE;2-Piperidineacetic acid hydrochloride;2-Piperidylacetic Acid Hydrochloride;2-Piperidineacetic acid HCl
• CAS NO: 19615-30-6
• Molecular Formula: C₇H₁₃NO₂*ClH
• Molecular Weight: 179.64
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Piperidines;Building Blocks;C5 to C7;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 19615-30-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 183-186 °C(lit.)
• Boiling Point: 318.1°C at 760 mmHg
• Flash Point: 146.2°C
• Appearance: /
• Vapor Pressure: 7.77E-05mmHg at 25°C
• CAS DataBase Reference: PIPERIDIN-2-YL-ACETIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: PIPERIDIN-2-YL-ACETIC ACID HYDROCHLORIDE(19615-30-6)
• EPA Substance Registry System: PIPERIDIN-2-YL-ACETIC ACID HYDROCHLORIDE(19615-30-6)

Safety Data

• Hazard Codes: C,Xn
• Statements: 20/21/22-34-41-22
• Safety Statements: 26-36/37/39-45-39
• RIDADR: UN 1759 8/PG 3
• WGK Germany: 2
• Hazardous Substances Data: 19615-30-6(Hazardous Substances Data)

Usage

Uses

Reactant for:? ;Enantiopure piperidine based β-amino esters via chemoenzymatic approach1? ;Esterification2

InChI:InChI=1/C7H13NO2.ClH/c9-7(10)5-6-3-1-2-4-8-6;/h6,8H,1-5H2,(H,9,10);1H

Upstream product

• 16179-97-8 pyridin-2-yl acetic acid hydrochloride 
• 61020-07-3 1-formyl-2-methoxy-piperidine 
• 13115-43-0 2-pyridineacetic acid 
• 71602-43-2 dimethyl (1-formyl-2-piperidyl)-malonate 

Downstream Products

• 1190970-17-2 1-(2-(pyridin-4-yl)-6,7-dihydrothiazolo[5,4-c]pyridin-5(4H)-yl)-2-(1-(3-(trifluoromethyl)phenylsulfonyl)piperidin-2-yl)ethan-1-one 
• 1073696-63-5 2-[1-[[3-(Trifluoromethyl)phenyl]sulfonyl]-piperidin-2-yl]-acetic acid 
• 1190971-02-8 [1-(3-trifluoromethyl-benzenesulfonyl)-piperidin-2-yl]-acetic acid methyl ester 
• 23692-08-2 piperidin-2-yl-acetic acid methyl ester 
• 183859-36-1 methyl (+/-)-N-(tert-butyloxycarbonyl)piperidin-2-ylacetate 
• 813433-73-7 (R)-2-methoxycarbonylmethylpiperidine-1-carboxylic acid tert-butyl ester 
• 131134-77-5 (S)-2-(methoxycarbonylmethyl)piperidine-1-carboxylic acid tert-butyl ester 
• 934422-89-6 [1-(2-nitro-benzenesulfonyl)-piperidin-2-yl]-acetic acid methyl ester 
• 934422-94-3 2-methoxycarbonylmethyl-piperidine-1-carboxylic acid benzyl ester 
• 169384-56-9 2-methoxycarbonylmethyl-piperidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

SUBSTITUTED SULFONAMIDE DERIVATIVES

The invention relates to substituted sulfonamide derivatives, processes for the preparation thereof, medicaments containing these compounds and the use of substituted sulfonamide derivatives for the preparation of medicaments.

Electrophilic Amidoalkylation of C-H Acidic Compounds with Cyclic N-Formylimmonium Precursors

C-H acidic compounds, such as esters of malonic acid, substituted malonic acids, 2-oxocyclopentanecarboxylic acid and acetoacetic acid and in some cases monocarbonyl compounds, e.g. acetone and cyclopentanone, react with cyclic N-formyl-N-α-methoxyamines,