19655-72-2Relevant academic research and scientific papers
AMIDINE COMPOUNDS
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Page 39, (2008/06/13)
Amidine derivatives of opioids of the formula YN-X-(NH)n-C(=NR)-R' in which YN is a morphine-like opioid radical; X is a direct bond, a substituted or unsubstituted, branched, straight-chained or cyclic alkylene having from 1 to 6 carbon atoms, optionally containing one or two heteroatoms in the alkyl chain, or an optionally substituted, branched or straight-chained alkenylene having from 4 to 10 carbon atoms; R and R' are independently hydrogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, substituted alkyne, aryl, substituted aryl, heterocycle, substituted heterocycle or cyano; and n is 0 when X is said direct bond, or n is 1 when X is said alkylene or alkenylene. The compounds are effective in treating pain, and have effect in the peripheral nervous system, with comparably less or no activity in the central nervous system.
IMIDOYLBENZOTRIAZOLES: STABLE ALTERNATIVES TO IMIDOYL CHLORIDES
Katritzky, Alan R.,Stevens, Christian V.,Zhang, Gui-Fen,Jiang, Jinlong,Kimpe, Norbert De
, p. 231 - 240 (2007/10/02)
Imidoylbenzotriazoles were prepared from the corresponding amides and 1,1'-sulfinyldibenzotriazole, generated in situ from 1-trimethylsilylbenzotriazole and thionyl chloride.The imidoylbenzotriazoles are stable precursors for the synthesis of imidates and
Monomeric Metaphosphate Anion: Reaction with Carbonyl Groups
Satterthwait, Arnold C.,Westheimer, F. H.
, p. 1177 - 1180 (2007/10/02)
The elusive monomeric metaphosphate anion is generated rapidly at room temperature by the fragmentation of threo- or erythro- (1,2-dibromo-1-phenylpropyl)phosphonate in the presence of a hindered base; it reacts at the carbonyl groups of acetophenone and
