196597-16-7

Basic information

• Product Name: N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionaMide
• Synonyms: N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acetaMide;AcetaMide, N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]-;ramelteon impurity E;Ramelteon Impurity B;Ramelteon Impurity 2;N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)acetamide
• CAS NO: 196597-16-7
• Molecular Formula: C16H21NO2
• Molecular Weight: 259.34344
• Mol File: 196597-16-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 78-79 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Boiling Point: 446.0±24.0 °C(Predicted)
• Appearance: /
• Density: 1.140±0.06 g/cm3(Predicted)
• PKA: 16.37±0.46(Predicted)
• CAS DataBase Reference: N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionaMide(196597-16-7)
• EPA Substance Registry System: N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionaMide(196597-16-7)

Safety Data

• Hazardous Substances Data: 196597-16-7(Hazardous Substances Data)

Usage

General Description

N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionamide is a chemical compound with the molecular formula C18H23NO2. It is a propionamide derivative that contains a tetrahydro-1H-indeno[5,4-b]furan-8-yl group. N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionamide may have potential applications in the field of medicinal chemistry, as propionamide derivatives have been studied for their pharmacological properties, including anti-inflammatory and analgesic effects. Further research is needed to fully understand the chemical and biological properties of N-(2-(2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl)propionamide and its potential uses in various industries.

Upstream product

• 196597-78-1 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one 
• 75-36-5 acetyl chloride 
• 196597-65-6 ethyl (E)-3-(2,3-dihydrobenzofuran-5-yl)-2-propenoate 
• 196597-66-7 ethyl 3-(2,3-dihydro-1-benzofuran-5-yl)propanoate 
• 227179-21-7 3-(6,7-dibromo-2,3-dihydro-benzofuran-5-yl)-propionyl chloride 
• 196597-76-9 ethyl 3-(6,7-dibromo-2,3-dihydrobenzofuran-5-yl) propionic acid 
• 196597-77-0 4,5-dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one 
• 196597-79-2 (E)-2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile 
• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 
• 108-24-7 acetic anhydride 
• 496-16-2 2.3-dihydrobenzofuran 
• 448964-37-2 2?(1,6,7,8?tetrahydro?2H?indeno[5,4?b]furan?8?yl)?1?ethylamine 
• 196597-75-8 ethyl 3-(6,7-dibromo-2,3-dihydro-1-benzofuran-5-yl)propanoate 
• 196597-67-8 ethyl 3-(7-bromo-2,3-dihydro-1-benzofuran-5-yl)propanoate 

Relevant articles and documents

Efficient synthesis of [11C]ramelteon as a positron emission tomography probe for imaging melatonin receptors involved in circadian rhythms

Ramelteon (TAK-375) is a novel melatonin receptor agonist that is used for clinical treatment of insomnia. The present report describes radiolabeling of ramelteon with the short-lived positron-emitter 11C (T 1/2=20.4 min) by 2 method

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A stabilized preparation which comprises: a unstable drug in a polyethylene glycol-containing preparation; and a coating agent comprising a copolyvidone instead of polyethylene glycol with which the drug is coated.

PERCUTANEOUS ABSORPTION AGENTS

Percutaneous absorption preparations which make it possible to absorb compounds having a melatonin receptor agonist activity via a convenient administration system, have favorable blood-drug-concentration-time profile and can exert a therapeutic effect on a disease caused by a decrease in secretion of melatonin at night.