19679-59-5Relevant academic research and scientific papers
Synthesis of isoquinolines via Rh(III)-catalyzed C-H activation using hydrazone as a new oxidizing directing group
Chuang, Sheng-Chieh,Gandeepan, Parthasarathy,Cheng, Chien-Hong
supporting information, p. 5750 - 5753 (2013/12/04)
An efficient and mechanistically interesting method for the synthesis of highly substituted isoquinolines by a Rh(III)-catalyzed hydrazone directed ortho C-H bond activation and annulation without an external oxidant is described. This reaction is accomplished via a C-C and C-N bond formation along with N-N bond cleavage.
Regio- and stereoselectivity in the cyclization of enolates derived from 4,5-, 5,6-, and 6,7-epoxy-1-phenyl-1-alkanones. Competition between C- and O- alkylation
Crotti, Paolo,Di Bussolo, Valeria,Favero, Lucilla,Macchia, Franco,Pineschi, Mauro,Napolitano, Elio
, p. 5853 - 5866 (2007/10/03)
The results obtained in the base-catalyzed intramolecular cyclization of enolates derived from some representative 4,5-, 5-6, and 6,7-epoxy ketones and of the corresponding alkenes are discussed. The LHMDS/Sc(OTf)3 protocol on epoxy ketones app
Synthese de methyl-8 dehydro-1,2 pyrrolizidines et de methyl-9 dehydro-1,2 indolizidines
Abbas, S. A.,Laurent, A.,Mison, P.,Pellissier, N.
, p. 288 - 296 (2007/10/02)
A synthetic route to the title compounds is described.It is based on the intramolecular cyclisation of hydroxy-Δ-3-pyrrolines 9, which are prepared in two steps from 2H-pyrroles 4.The stereoselectivity of the sequence can be controlled by changing the order of these two steps.
