93472-51-6

Basic information

• Product Name: Isoquinoline, 1-ethyl-3,4-diphenyl-
• CAS NO: 93472-51-6
• Molecular Formula: C23H19N
• Molecular Weight: 309.411
• Mol File: 93472-51-6.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: Isoquinoline, 1-ethyl-3,4-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline, 1-ethyl-3,4-diphenyl-(93472-51-6)
• EPA Substance Registry System: Isoquinoline, 1-ethyl-3,4-diphenyl-(93472-51-6)

Safety Data

• Hazardous Substances Data: 93472-51-6(Hazardous Substances Data)

Upstream product

• 501-65-5 diphenyl acetylene 
• 75-05-8 acetonitrile 
• 19679-59-5 propiophenone N,N-dimethylhydrazone 
• 93-55-0 1-phenyl-propan-1-one 
• 1426021-96-6 (E)-1-phenylpropan-1-one O-acetyl oxime 
• 60295-07-0 N'-[1-Phenyl-prop-(Z)-ylidene]-hydrazinecarboxylic acid tert-butyl ester 
• 2941-20-0 1-phenylpropylamine 
• 17336-66-2 propiophenone N-tosylhydrazone 
• 631-61-8 ammonium acetate 
• 2157-50-8 propiophenone oxime 
• 1607-57-4 Triphenylvinyl bromide 
• 107-12-0 propiononitrile 

Relevant articles and documents

Rh(III)?catalyzed synthesis of isoquinolines from N-hydroxyoximes and alkynes in γ-valerolactone

A Rh (III)?catalyzed synthesis of isoquinoline derivatives from N-hydroxyoximes and alkynes via C–H activation/annulation process in biomass-derived γ-valerolactone (GVL) has been developed. A series of functional groups were well tolerated, affording the desired products in good to excellent yields.

Ruthenaelectro-Catalyzed Domino Three-Component Alkyne Annulation for Expedient Isoquinoline Assembly

The electrochemical three-component assembly of isoquinolines has been accomplished by ruthenaelectro-catalyzed C?H/N?H functionalization. The robustness of the electrocatalysis was reflected by an ample substrate scope, an efficient electrooxidation, and an operationally friendly procedure. The isolation of key intermediates and detailed mechanistic studies, including unprecedented cyclovoltammetric analysis of a seven-membered ruthenacycle, provided support for an unusual ruthenium(II/III/I) regime.

Rh(III)-catalyzed synthesis of isoquinolines using the N-Cl bond of N-chloroimines as an internal oxidant

The Rh(III)-catalyzed coupling of N-chloroimines with alkynes for the efficient synthesis of isoquinolines is reported. This represents the first use of the N-Cl bond of N-chloroimines as an internal oxidant for construction of the isoquinoline skeleton. The synthesis features atom and step economy, a green solvent (EtOH), mild reaction conditions, and a broad substrate scope.