19686-05-6

Basic information

• Product Name: 2,8-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
• Synonyms: 2,8-dimethyl-1,3,4,5-tetrahydropyrido[4,3-b]indole;5-23-07-00381 (Beilstein Handbook Reference);BAS 01530386;BRN 0958096;CBDivE_010708;Oprea1_301007;Oprea1_561845;Probes1_000106
• CAS NO: 19686-05-6
• Molecular Formula: C13H16N2
• Molecular Weight: 200.28
• EINECS: 1312995-182-4
• Mol File: 19686-05-6.mol
• Article Data: 32

Chemical Properties

• Melting Point: 156-158°C
• Boiling Point: 342.1 °Cat760mmHg
• Flash Point: 160.7 °C
• Appearance: /
• Density: 1.137 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: 2-8°C
• PKA: 17.59±0.20(Predicted)
• CAS DataBase Reference: 2,8-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,8-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(19686-05-6)
• EPA Substance Registry System: 2,8-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(19686-05-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 19686-05-6(Hazardous Substances Data)

Usage

Uses

2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

InChI:InChI=1/C13H16N2/c1-9-3-4-12-10(7-9)11-8-15(2)6-5-13(11)14-12/h3-4,7,14H,5-6,8H2,1-2H3

Upstream product

• 112-35-6 triethylene glucol monomethyl ether 
• 107-05-1 3-chloroprop-1-ene 
• 106-95-6 allyl bromide 
• 1445-73-4 1-Methyl-4-piperidone 
• 501-60-0 1,2-di(p-tolyl)diazene 
• 95-74-9 3-chloro-p-toluidine 
• 1346446-47-6 (3-chloro-4-methylphenyl)-(1-methylpiperidin-4-ylidene)amine 
• 1692-25-7 3-pyridylboronic acid 
• 583-68-6 2-bromo-p-toluidine 
• 695185-44-5 3-(2-amino-5-methylphenyl)pyridine 
• 1296770-97-2 CF₃O₃S^(1-)*C₁₃H₁₃N₂⁽¹⁺⁾ 
• 1296770-72-3 1-methyl-3-(2-azido-5-methylphenyl)pyridinium triflate 
• 1296770-62-1 3-(2-azido-5-methylphenyl)pyridine 
• 637-60-5 p-tolylhydrazine hydrochloride 

Downstream Products

• 1147893-10-4 5-benzyl-2,3,4,5-tetrahydro-2,8-dimethyl-1H-pyrido[4,3-b]indole trifluoroacetate 
• 1147892-90-7 2,3,4,5-tetrahydro-2,8-dimethyl-5-(4-methylphenethyl)-1H-pyrido[4,3-b]indole trifluoroacetate salt 
• 28683-48-9 2,8-dimethyl-5-[2-(pyridin-4-yl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1147863-96-4 5-(2-(4-ethoxyphenyl)ethyl)-2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1147892-97-4 5-(4-chlorophenethyl)-2,3,4,5-tetrahydro-2,8-dimethyl-1H-pyrido[4,3-b]indole 
• 1147863-94-2 5-(2-(4-isopropoxyphenyl)ethyl)-2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1147893-15-9 2-(1,2,3,4-tetrahydro-2, 8-dimethylpyrido[4,3-b]indol-5-yl)-1-p-tolylethanol hydrochloride 
• 1147863-98-6 5-(2-(4-tert-butoxyphenyl)ethyl)-2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1147864-58-1 methyl 2-(6-trifluoromethylpyridin-3-yl)-3-(1,2,3,4-tetrahydro-2,8-dimethylpyrido[4,3-b]indol-5-yl)propanoate 
• 19690-43-8 2,8-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride 
• 1225268-96-1 2-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)-1-(4-fluorophenyl)ethanone 

Relevant articles and documents

Double "open and Shut" Transformation of γ-Carbolines Triggered by Ammonium Salts: One-Pot Synthesis of Multiheterocyclic Compounds

A novel cascade reaction of indole-2,3-epoxide equivalents with γ-carbolines by utilizing a double "open and shut" transformation to access multiheterocyclic compounds containing both isotryptamines and pyrimido[1,6-a]indoles has been developed. This strategy utilizes the in situ formation of a bulky quaternary ammonium salt via ammonium exchange, which undergoes Hofmann elimination/vinylogous Mannich/retro-Mannich/cyclization cascade sequences.

Direct Synthesis of Indoles from Azoarenes and Ketones with Bis(neopentylglycolato)diboron Using 4,4′-Bipyridyl as an Organocatalyst

Multifunctionalized indole derivatives were prepared by reducing azoarenes in the presence of ketones and bis(neopentylglycolato)diboron (B2nep2) with a catalytic amount of 4,4′-bipyridyl under neutral reaction conditions, where 4,4′-bipyridyl acted as an organocatalyst to activate the B-B bond of B2nep2 and form N,N′-diboryl-1,2-diarylhydrazines as key intermediates. Further reaction of N,N′-diboryl-1,2-diarylhydrazines with ketones afforded N-vinyl-1,2-diarylhydrazines, which rearranged to the corresponding indoles via the Fischer indole mechanism. This organocatalytic system was applied to diverse alkyl cyclic ketones, dialkyl, and alkyl/aryl ketones, including heteroatoms. Methyl alkyl ketones gave the corresponding 2-methyl-3-substituted indoles in a regioselective manner. This protocol allowed us to expand the preparation of indoles having high compatibility with not only electron-donating and electron-withdrawing groups but also N- and O-protecting functional groups.

Anion Receptor, Electrolyte Containing the Anion Receptor and Lithium Ion Battery and Lithium Ion Capacitor Using the Electrolyte

The present invention relates to a novel anion acceptor having a high cation transport rate and improved lifespan, an electrolyte containing the same, and a lithium ion battery and a lithium ion capacitor manufactured using the electrolyte and, more specifically, to a compound represented by chemical formula 1. In the chemical formula 1, n is an integer from 1 to 50, and X is one or more selected from the group consisting of -NR_1R_2, -NR_3R_4, -Ph(-(m)-R_5), and -O-(CH_2CH_2O)_y-CH_3.COPYRIGHT KIPO 2018