196872-91-0

Basic information

• Product Name: 8-methyl-4-phenyl-2-phenylquinoline
• Synonyms: 8-methyl-4-phenyl-2-phenylquinoline
• CAS NO: 196872-91-0
• Molecular Weight: 295.384
• Mol File: 196872-91-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 8-methyl-4-phenyl-2-phenylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methyl-4-phenyl-2-phenylquinoline(196872-91-0)
• EPA Substance Registry System: 8-methyl-4-phenyl-2-phenylquinoline(196872-91-0)

Safety Data

• Hazardous Substances Data: 196872-91-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 536-74-3 phenylacetylene 
• 95-53-4 o-toluidine 
• 98-80-6 phenylboronic acid 
• 5405-13-0 N-benzyl-2-methylaniline 
• 4891-38-7 phenylpropynoic acid methyl ester 
• 34143-86-7 N-((E)-benzylidene)-o-toluidine 
• 60-12-8 2-phenylethanol 
• 5877-55-4 N-benzylidene-2-methylaniline 
• 614-47-1 1,3-diphenyl-propen-3-one 

Relevant articles and documents

Mn(III)-Mediated Regioselective 6-endo-trig Radical Cyclization of o-Vinylaryl Isocyanides to Access 2-Functionalized Quinolines

A Mn(III)-mediated radical cyclization reaction of o-vinylaryl isocyanides and arylboronic acids or diphenylphosphine oxides to access various 2-functionalized quinolines under mild conditions was developed. With the introduction of radical stabilizing substituents (e. g. aryl and methyl group) on vinyl group, this reaction provides a regiospecific 6-endo-trig radical cyclization of o-vinylaryl isocyanides, giving a number of structurally unique and biologically potential 2-functionalized quinoline derivatives.

One-pot synthesis of 2,4-disubstituted quinolines via silver-catalyzed three-component cascade annulation of amines, alkyne esters and terminal alkynes

Described herein is a new and general method for one-pot synthesis of 2,4-disubstituted quinolines via silver-catalyzed [3 + 1 + 2] annulation of simple amines, alkyne esters and terminal alkynes. The versatile transformation might initiate with the facil

Microwave-Assisted Metal-Free Rapid Synthesis of C4-Arylated Quinolines via Povarov Type Multicomponent Reaction

A rapid microwave assisted, (±) camphor-10-sulfonic acid (CSA) promoted, Povarov type multicomponent synthesis of 4-arylated quinolines from anilines, alkynes, and paraformaldehyde is described. This reaction proceeds through [4+2] cycloaddition of imine (formed in situ from aniline and paraformaldehyde) and alkynes in the presence of CSA, without any metal catalyst. Mechanistic study revealed that CSA inhibit the synthesis of Troger's base and assist the cycloaddition of imines with alkynes by activating the imine.