19689-20-4Relevant articles and documents
Mesoporous SBA-15 supported silver nanoparticles as environmentally friendly catalysts for three-component reaction of aldehydes, alkynes and amines with glycol as a "green" solvent
Yong, Guo-Ping,Tian, Dong,Tong, Hong-Wu,Liu, Shao-Min
, p. 40 - 44 (2010)
The mesoporous SBA-15 supported silver nanoparticles catalyst system with a highly ordered hexagonal mesostructure was prepared by an in situ reduction method using hexamethylenetetramine as mild and efficient reducing agent. These AgSBA-15 materials act
PROPARGYLAMINE SYNTHESIS USING A COPPER (I) CATALYSED THREE COMPONENT COUPLING REACTION
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Page/Page column 10; 12, (2012/02/01)
The present invention relates to a three component coupling reaction. In this reaction a terminal alkyne or a salt thereof, a geminal dihalide and a primary or secondary amine are reacted in the presence of a copper (I) catalyst to produce a propargylamin
Cobalt-catalyzed alkyne-dihalomethane-amine coupling: An efficient route for propargylamines
Tang, Yanchi,Xiao, Tiebo,Zhou, Lei
supporting information, p. 6199 - 6201,3 (2012/12/12)
A cobalt-catalyzed three-component coupling of terminal alkynes, dihalomethanes, and amines was developed. This method offers an efficient way for propargylamines via the dual activation of C-H and C-halogen bond. The reaction uses cheap CoBr2
Copper-catalyzed three-component coupling of terminal alkyne, dihalomethane and amine to propargylic amines
Yu, Dingyi,Zhang, Yugen
experimental part, p. 163 - 169 (2011/03/22)
The direct C-H and C-halogen activation for C-C bond formation is one of the most interesting reactions in organic chemistry. C-C bond formation using alkynes as a carbon nucleophilic source is a very useful method in synthesis. Herein, a copper(I) chlori
Silver nanoparticles supported by novel nickel metal-organic frameworks: An efficient heterogeneous catalyst for an A3 coupling reaction
Wang, Sujing,He, Xiaoxiao,Song, Lexin,Wang, Zhiyong
scheme or table, p. 447 - 450 (2009/07/25)
A novel heterogeneous catalyst of silver nanoparticles was prepared by using a nickel metal-organic framework (Ni-MOF) as a template. The catalyst has a very high catalytic activity and a strict structural selectivity towards linear aliphatic aldehydes in
Mild and efficient synthesis of propargylamines by copper-catalyzed Mannich reaction
Bieber, Lothar W.,Da Silva, Margarete F.
, p. 8281 - 8283 (2007/10/03)
Terminal alkynes can be condensed with aqueous formaldehyde and primary or secondary amines to give secondary and tertiary propargylamines. The reaction is best carried out in DMSO under CuI catalysis. Terminal alkynes undergo mild and efficient aminomethylation with aqueous formaldehyde and secondary amines under CuI catalysis. In most cases high to nearly quantitative yields of tertiary propargylamines are obtained in DMSO solution at room temperature. Aromatic, aliphatic and silylated acetylenes as well as alkynols can be used. Primary amines are less reactive and satisfactory yields of secondary propargylamines are obtained only with phenylacetylene.