196960-06-2

Upstream product

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 38573-88-5 1-bromo-2,3-difluorobenzene 
• 196960-05-1 8-(2,3-difluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene 
• 1283606-46-1 8-(2,3-difluorophenyl)-1,4-dioxaspiro[4.5]decane 
• 170011-47-9 1,4-dioxaspiro[4.5]dec-7-en-8-yl trifluoromethanesulfonate 
• 367-11-3 ortho-difluorobenzene 
• 680596-79-6 4,4,5,5-tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1,3,2-dioxaborolane 

Downstream Products

• 1338448-92-2 1-butoxy-4-[4-(2,3-difluorophenyl)cyclohex-1-enyl]-2,3-difluorobenzene 
• 1338444-62-4 1-butoxy-4-(4-(4-(4-(2,3-difluoro-4-hexyloxyphenyl)cyclohex-1-enyl)-2,3-difluorophenyl)cyclohex-1-en yl)-2,3-difluorobenzene 

Relevant academic research and scientific papers

NOVEL 5 or 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS SELECTIVE INHIBITORS OF INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES

Disclosed herein are 5 or 8-substituted imidazo [1, 5-a] pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo [1, 5-a] pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8-substituted imidazo [1, 5-a] pyridines that can be useful for inhibiting indoleamine 2, 3-dioxygenase and/or tryptophane 2, 3-dioxygenase and for treating diseases or disorders mediated thereby.

Ethyleneoxy-containing compound, and composition and application thereof

The invention discloses a compound, wherein a structure of the compound is represented by the general formula I. The compound has negative dielectric anisotropism. The compound has stable structure and properties, has the characteristics of negative dielectric anisotropism with large absolute value and good compatibility with other liquid crystal components, and can be widely applied to liquid crystal display devices. A liquid crystal composition containing the compound can be applied to the liquid crystal display devices and has a significantly large voltage retention rate.

SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF

Provided is a substituted piperidine compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an orexin type 2 receptor agonist act

LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT

The invention provides a liquid crystal compound having general physical properties necessary for the liquid crystal compound, namely, stability to heat, light and so forth, a small viscosity, a refractive index anisotropy having a suitable magnitude value, a dielectric anisotropy having a suitable magnitude value, steep electrooptical characteristics, a wide temperature range of a nematic phase, and an excellent compatibility with other liquid crystal compounds, in particular, a liquid crystal compound having a wide temperature range of the nematic phase; a compound represented by formula (i): wherein, for example, R1 and R2 are alkyl having 1 to 8 carbons or alkenyl having 2 to 8 carbons; ring A1 is trans-1,4-cyclohexylene or 1,4-phenylene; ring A2 is trans-1,4-cyclohexylene or 2,3-difluoro-1,4-phenylene; Q1 and Q2 are fluorine or chlorine; and h is 0, 1 or 2.