197230-34-5

Upstream product

• 127793-67-3 (S)‐7‐(benzyloxy)hept‐1‐en‐4‐ol 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 1346132-33-9 benzyl-(2R)-2-(2’-oxopropyl) pyrrolidine-1-carboxylate 
• 1597449-89-2 (2R,2′R,S_S)-(N-benzyloxycarbonyl)-2-[2′-(tert-butylsulfinamine)-4′-pentenyl]pyrrolidine 
• 1036404-01-9 (R)-(N-benzyloxycarbonyl)-2-(2-oxoethyl)pyrrolidine 
• 1597449-90-5 (2R,2′S,R_S)-(N-benzyloxycarbonyl)-2-[(2′-tert-butylsulfinamine)-4′-pentenyl]pyrrolidine 
• 496-47-9 (+)-hygroline 
• 197230-44-7 (2S-(2R))-1-benzyloxycarbonyl-2-(2,3-epoxypropyl)pyrrolidine 
• 197229-88-2 (2R-(2S))-1-benzyloxycarbonyl-2-(2,3-epoxypropyl)pyrrolidine 
• 197230-42-5 (2R-(2R))-1-benzyloxycarbonyl-2-(2,3-epoxypropyl)pyrrolidine 
• 197230-36-7 (2R-(2R))-1-benzyloxycarbonyl-2-(2,3-dihydroxypropyl)pyrrolidine 
• 197230-38-9 (2S-(2R))-1-benzyloxycarbonyl-2-(2,3-dihydroxypropyl)pyrrolidine 
• 197229-68-8 N-(benzyloxycarbonyl)-(5R)-5-[(2S)-2,3-dihydroxyprop-1-yl]pyrrolidine 

Relevant academic research and scientific papers

New synthesis of all the four isomers of 2-(2-hydroxypropyl)pyrrolidines via iterative asymmetric dihydroxylation to cause enantiomeric enhancement

Both enantiomers of 2-(2-propenyl)pyrrolidine 7 (75-84% ee), prepared via the asymmetric dihydroxylation (AD) of terminal olefin 5, underwent the second AD to provide all of the four stereoisomeric 2-(2-hydroxypropyl)pyrrolidines 8 with enantiomeric enhan

An enantioselective synthesis of (+)-hygroline and (+)-pseudohygroline via Keck allylation and CBS reduction

Abstract An enantioselective synthesis of (+)-hygroline and (+)-pseudohygroline has been achieved in high optical purity (98% ee) from readily available 1,4-butanediol. The synthesis strategy employs a Keck allylation, CBS reduction, and Wacker oxidation.