New synthesis of all the four isomers of 2-(2-hydroxypropyl)pyrrolidines via iterative asymmetric dihydroxylation to cause enantiomeric enhancement

DOI: 10.1016/S0957-4166(97)00348-0

Source and publish data:

Tetrahedron Asymmetry p. 2801 - 2810 (1997)

Update date:2022-08-03

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Authors:

Takahata, Hiroki

Kubota, Minoru

Momose, Takefumi

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Article abstract of DOI:10.1016/S0957-4166(97)00348-0

Both enantiomers of 2-(2-propenyl)pyrrolidine 7 (75-84% ee), prepared via the asymmetric dihydroxylation (AD) of terminal olefin 5, underwent the second AD to provide all of the four stereoisomeric 2-(2-hydroxypropyl)pyrrolidines 8 with enantiomeric enhan

Full text of DOI:10.1016/S0957-4166(97)00348-0

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